Calprotectin, Fecal
Test Mnemonic
CALPRO
CPT Codes
- 83993 - QTY (1)
LOINC ®
38445-3
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 5 g | Stool, random | Sterile container | Refrigerated | Container should be preservative free |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 g | Container should be preservative free |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 6 hours |
| Frozen | 16 weeks |
| Refrigerated | 14 days |
Days Performed
Mon - Fri
Turnaround Time
2 - 4 days
Methodology
| Name | Description |
|---|---|
| Chemiluminescence Immunoassay (CLIA) |
Reference Range
| Fecal Calprotectin Concentration | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | <50 | ug/g | |||
| Fecal Calprotectin Interpretation | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | Normal |
Clinical Info
The quantitative detection of calprotectin is an in vitro diagnostic test to aid in the diagnosis of inflammatory bowel disease (IBD) in conjunction with other clinical and laboratory findings. Fecal calprotectin is an indicator of neutrophils in the stool and is not specific for IBD. Elevations in fecal calprotectin may be caused by proton pump inhibitors, non-steroid-anti-inflammatory-drugs, and intestinal impairments other than IBD (e.g., diverticulitis, celiac disease, infections, cancer).