Carbamazepine and Metabolite
Test Mnemonic
CARBME
CPT Codes
- 80156 - QTY (1)
- 80161 - QTY (1)
Aliases
- Carbarbamazepine 10,11-Epoxide & Total Carbamazepine
- Tegretol & Metabolite
Includes
- Carbamazepine
- Carbamazepine-10,11-Epoxide
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 3 mL | Plasma | Green LiHep Nogel | Refrigerated | Do not collect in a gel separator tube. Centrifuge and transfer the plasma to a plastic CCL tube within 2 hours of collection and refrigerate. Transport and store at refrigerated temperature. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 3 mL | Serum | No additive (Red) | Refrigerated | Do not collect in a gel separator tube. Centrifuge and transfer the serum to a plastic CCL tube within 2 hours of collection and refrigerate. Transport and store at refrigerated temperature. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | Unacceptable |
| Frozen | After separation from cells: 1 month |
| Refrigerated | After separation from cells: 1 week |
Days Performed
Mon - Sat
Turnaround Time
1 - 3 days
Methodology
| Name | Description |
|---|---|
| Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) | |
| Kinetic Interaction of Microparticles in a Solution |
Reference Range
| Carbamazepine | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 99 Years | Normal | 4.0 - 12.0 | ug/mL | Years | 99 Years | Urgent | > 15.0 | ug/mL |
| Carbamazepine-10,11-Epoxide | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | Optimal Concentration: 1.4 - 5.9 | ug/mL | Years | 99 Years | Urgent | > 15.0 | ug/mL |
Special Info
Collect specimen immediately prior to next dose.
Clinical Info
Monitor therapeutic administration.