Chlamydia Antibodies Evaluation




Test Mnemonic

CIGIM

CPT Codes

  • 86632 - QTY (3)
  • 86631 - QTY (3)

LOINC ®

16589-4

Aliases

  • Chlamydia spp IgG, IgM Abs
  • Chlamydia TWAR Abs

Includes

  • Chlamydia pneumoniae IgG
  • Chlamydia pneumoniae IgM
  • Chlamydia psittaci IgG
  • Chlamydia psittaci IgM
  • Chlamydia trachomatis IgG
  • Chlamydia trachomatis IgM

Performing Laboratory

ARUP


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mLSerumSST (Gold) RefrigeratedParallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute specimens. Label specimens plainly as 'acute' or 'convalescent.' Separate serum from cells ASAP or within 2 hours of collection and transfer into standard aliquot tube.

Alternate Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mLSerumNo additive (Red) RefrigeratedParallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute specimens. Label specimens plainly as 'acute' or 'convalescent.' Separate serum from cells ASAP or within 2 hours of collection and transfer into standard aliquot tube.

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.4 mL     

Stability

Environmental Condition Description
AmbientAfter separation from cells: 48 hours
RefrigeratedAfter separation from cells: 2 weeks
FrozenAfter separation from cells: 1 year (Avoid repeated freeze/thaw cycles)

Days Performed

Sun - Fri

Turnaround Time

2 - 5 days

Methodology

Name Description
Semi-Quantitative Indirect Fluorescent Antibody 

Reference Range

C. pneumoniae IgG Titer
Sex Age From Age To Type Range Range Unit
       < 1:64 
C. pneumoniae IgM Titer
Sex Age From Age To Type Range Range Unit
       < 1:20 
C. psittaci IgG Titer
Sex Age From Age To Type Range Range Unit
       < 1:64 
C. psittaci IgM Titer
Sex Age From Age To Type Range Range Unit
       < 1:20 
C. trachomatis IgG Titer
Sex Age From Age To Type Range Range Unit
       < 1:64 
C. trachomatis IgM Titer
Sex Age From Age To Type Range Range Unit
       < 1:20 

Special Info

Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute specimens. Label specimens plainly as 'acute' or 'convalescent.' Contaminated, hemolyzed, or hyperlipemic sera will be rejected. This test is New York DOH approved.

Clinical Info

Used to differentiate between Chlamydophila species (C. psittaci, C. pneumoniae). Differentiate early IgM response to infection from persistent low-level titer. Because of cross-reactivity, a C. pneumoniae-specific reaction will exhibit titers two-fold or greater than C. trachomatis or C. psittaci serology. This has limited value in the diagnosis of most oculogenital (e.g., eyes, genitalia) chlamydial infections.