Chlamydia Antibodies Evaluation
Test Mnemonic
CIGIM
CPT Codes
- 86632 - QTY (3)
- 86631 - QTY (3)
LOINC ®
16589-4
Aliases
- Chlamydia spp IgG, IgM Abs
- Chlamydia TWAR Abs
Includes
- Chlamydia pneumoniae IgG
- Chlamydia pneumoniae IgM
- Chlamydia psittaci IgG
- Chlamydia psittaci IgM
- Chlamydia trachomatis IgG
- Chlamydia trachomatis IgM
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | SST (Gold) | Refrigerated | Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute specimens. Label specimens plainly as 'acute' or 'convalescent.' Separate serum from cells ASAP or within 2 hours of collection and transfer into standard aliquot tube. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | No additive (Red) | Refrigerated | Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute specimens. Label specimens plainly as 'acute' or 'convalescent.' Separate serum from cells ASAP or within 2 hours of collection and transfer into standard aliquot tube. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.4 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | After separation from cells: 48 hours |
| Refrigerated | After separation from cells: 2 weeks |
| Frozen | After separation from cells: 1 year (Avoid repeated freeze/thaw cycles) |
Days Performed
Sun - Fri
Turnaround Time
2 - 5 days
Methodology
| Name | Description |
|---|---|
| Semi-Quantitative Indirect Fluorescent Antibody |
Reference Range
| C. pneumoniae IgG Titer | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| < 1:64 | |||||
| C. pneumoniae IgM Titer | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| < 1:20 | |||||
| C. psittaci IgG Titer | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| < 1:64 | |||||
| C. psittaci IgM Titer | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| < 1:20 | |||||
| C. trachomatis IgG Titer | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| < 1:64 | |||||
| C. trachomatis IgM Titer | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| < 1:20 |
Special Info
Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute specimens. Label specimens plainly as 'acute' or 'convalescent.' Contaminated, hemolyzed, or hyperlipemic sera will be rejected. This test is New York DOH approved.
Clinical Info
Used to differentiate between Chlamydophila species (C. psittaci, C. pneumoniae). Differentiate early IgM response to infection from persistent low-level titer. Because of cross-reactivity, a C. pneumoniae-specific reaction will exhibit titers two-fold or greater than C. trachomatis or C. psittaci serology. This has limited value in the diagnosis of most oculogenital (e.g., eyes, genitalia) chlamydial infections.