Chromium, Urine




Test Mnemonic

UCHRO

CPT Codes

  • 82495 - QTY (1)

Includes

  • Chromium, Urine ratio to CRT
  • Chromium, Urine per volume
  • Chromium, Urine per 24 hour
  • Creatinine, Urine per volume
  • Creatinine, Urine per 24 hour
  • Hours Collected
  • Total Volume

Performing Laboratory

ARUP


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
8 mLUrine, 24-hour (well-mixed)Plastic containerRefrigerate during collection.RefrigeratedPatient Prep: High concentrations of iodine may interfere with testing. Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, non-essential over-the-counter medications (upon the advice of their physician). Avoid iodinated or gadolinium-based contrast media for at least 72 hours or 14 days for patients with impaired kidney function. Collection: Collect in a plastic container, mix well and aliquot into a trace metal free transport tube (ARUP #43116). Record total volume and collection time interval on specimen.

Alternate Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
8 mLUrine, randomPlastic container RefrigeratedPatient Prep: High concentrations of iodine may interfere with testing. Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, non-essential over-the-counter medications (upon the advice of their physician). Avoid iodinated or gadolinium-based contrast media for at least 72 hours or 14 days for patients with impaired kidney function. Collection: Collect in a plastic container, mix well and aliquot into a trace metal free transport tube (ARUP #43116). Record total volume and collection time interval on specimen.

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mL     

Stability

Environmental Condition Description
Ambient1 week
Refrigerated2 weeks
Frozen1 year

Days Performed

Sun - Sat

Turnaround Time

2 - 6 days

Methodology

Name Description
Inductively Coupled Plasma / Mass Spectrometry (ICP-MS) 

Reference Range

Chromium, urine - per volume
Sex Age From Age To Type Range Range Unit
       Normal0.0 - 2.0ug/L
Chromium, urine (24hrs)
Sex Age From Age To Type Range Range Unit
       Normal0.0 - 2.0ug/d
Chromium, Urine ratio to CRT
Sex Age From Age To Type Range Range Unit
       Normal0.0 - 10.0ug/g crt

Special Info

Patient Prep: High concentrations of iodine may interfere with testing. Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, non-essential over-the-counter medications (upon the advice of their physician). Avoid iodinated or gadolinium-based contrast media for at least 72 hours or 14 days for patients with impaired kidney function. Collection: Collect in a plastic container, mix well and aliquot into a trace metal free transport tube (ARUP #43116). Record total volume and collection time interval on specimen. Urine transported in a non-trace element-free tube or contaminated with iodine, gadolinium, blood, fecal material or acid preservative will be rejected. This test is New York DOH approved.

Clinical Info

This test may be useful to monitor short term exposure. The form of chromium greatly influences distribution. Trivalent chromium resides in the plasma and is usually not of clinical importance. Hexavalent chromium is considered highly toxic. Symptoms associated with chromium toxicity vary based upon route of exposure and dose and may include dermatitis, impairment of pulmonary function, gastroenteritis, hepatic necrosis, bleeding, and acute tubular necrosis. The ACGIH Biological Exposure Index for daily exposure of hexavalent chromium is an increase of 10 µg/gCRT between pre-shift and post-shift urine collections. The ACGIH Biological Exposure Index for long and short-term hexavalent chromium is an end-of-shift concentration of 30 µg/gCRT at the end of the work week.