Chromium, Urine
Test Mnemonic
UCHRO
CPT Codes
- 82495 - QTY (1)
Includes
- Chromium, Urine ratio to CRT
- Chromium, Urine per volume
- Chromium, Urine per 24 hour
- Creatinine, Urine per volume
- Creatinine, Urine per 24 hour
- Hours Collected
- Total Volume
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 8 mL | Urine, 24-hour (well-mixed) | Plastic container | Refrigerate during collection. | Refrigerated | Patient Prep: High concentrations of iodine may interfere with testing. Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, non-essential over-the-counter medications (upon the advice of their physician). Avoid iodinated or gadolinium-based contrast media for at least 72 hours or 14 days for patients with impaired kidney function. Collection: Collect in a plastic container, mix well and aliquot into a trace metal free transport tube (ARUP #43116). Record total volume and collection time interval on specimen. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 8 mL | Urine, random | Plastic container | Refrigerated | Patient Prep: High concentrations of iodine may interfere with testing. Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, non-essential over-the-counter medications (upon the advice of their physician). Avoid iodinated or gadolinium-based contrast media for at least 72 hours or 14 days for patients with impaired kidney function. Collection: Collect in a plastic container, mix well and aliquot into a trace metal free transport tube (ARUP #43116). Record total volume and collection time interval on specimen. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 1 week |
| Refrigerated | 2 weeks |
| Frozen | 1 year |
Days Performed
Sun - Sat
Turnaround Time
2 - 6 days
Methodology
| Name | Description |
|---|---|
| Inductively Coupled Plasma / Mass Spectrometry (ICP-MS) |
Reference Range
| Chromium, urine - per volume | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | Less than or equal to 2.0 | ug/L | |||
| Chromium, urine (24hrs) | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | Less than or equal to 2.0 | ug/d | |||
| Chromium, Urine ratio to CRT | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | Less than or equal to 10.0 | ug/g crt |
Special Info
Patient Prep: Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, nonessential over-the-counter medications (upon the advice of their physician). High concentrations of iodine may interfere with testing. Avoid iodinated or gadolinium-based contrast media for at least 72 hours or 14 days for patients with impaired kidney function. Collection: Collect in a plastic container, mix well and aliquot into a trace metal free transport tube (ARUP #43116). Record total volume and collection time interval on specimen. Urine transported in a non-trace element-free tube or contaminated with iodine, gadolinium, blood, fecal material or acid preservative will be rejected. Elevated results may be due to skin or collection-related contamination, including the use of collection containers that are not certified to be trace element-free. Confirmation with a second specimen collected in a certified trace-element free container is recommended if an elevated result is suspected to be due to contamination. This test is New York DOH approved.
Clinical Info
This test may be useful to monitor short term exposure. The form of chromium greatly influences distribution. Trivalent chromium resides in the plasma and is usually not of clinical importance. Hexavalent chromium is considered highly toxic. Symptoms associated with chromium toxicity vary based upon route of exposure and dose and may include dermatitis, impairment of pulmonary function, gastroenteritis, hepatic necrosis, bleeding, and acute tubular necrosis. The ACGIH Biological Exposure Index for total chromium in urine is an end-of-shift concentration of 0.7 µg/L measured at the end of the work week.