Coenzyme Q10, Reduced and Total, Plasma
Test Mnemonic
COEQ10
CPT Codes
- 82542 - QTY (1)
Includes
- Coenz Q10 Reduced
- Coenz Q10 % Reduced
- Coenzyme Q10 Total
- CoQ10 Interpretation
Performing Laboratory
Mayo Clinic Dpt of Lab Med & Pathology
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL | Plasma | Sodium or Lithium heparin (Green) | Place specimen on ice after draw. | Frozen | Patient should fast for 8 hours prior to collection. Centrifuge, aliquot and freeze within 3 hours of collection. Separate specimens must be submitted when multiple tests are ordered. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.3 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Frozen | After separation from cells: 14 days |
| Refrigerated | After separation from cells: 8 hours |
| Ambient | Unacceptable |
Days Performed
Mon - Fri
Turnaround Time
4 - 6 days
Methodology
| Name | Description |
|---|---|
| High Performance Liquid Chromatography with Electrochemical Detection |
Reference Range
| Coenz Q10 % Reduced | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 17 Years | Normal | 93 - 100 | % | 18 Years | 99 Years | Normal | 92 - 98 | % |
| Coenz Q10 Reduced | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 17 Years | Normal | 320 - 1376 | mcg/L | 18 Years | 99 Years | Normal | 415 - 1480 | mcg/L |
| Coenzyme Q10 Total | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 17 Years | Normal | 320 - 1558 | mcg/L | 18 Years | 99 Years | Normal | 433 - 1532 | mcg/L |
Special Info
Patient should fast for 8 hours prior to collection. Separate specimens must be submitted when multiple tests are ordered. Failure to follow specimen handling guidelines may lead to false positive results. Grossly hemolyzed or lipemic specimens will be rejected. This test is New York DOH approved.
Clinical Info
This test is appropriate for the diagnosis of secondary coenzyme Q10 (CoQ10) deficiency and for some patients with primary CoQ10 deficiency who are not supplemented with CoQ10. It is also used to monitor CoQ10 status in patients with mitochondrial cytopathies, patients receiving statin therapy, or during treatment of various degenerative conditions including Parkinson and Alzheimer diseases.
Clinical Limitation
This test is not useful for distinguishing primary CoQ10 deficiencies from acquired CoQ10 deficiencies.