Collagen Type II Antibody
Test Mnemonic
CIIAB
CPT Codes
- 83520 - QTY (1)
Includes
- Collagen Type II Antibodies
Performing Laboratory
Mayo Clinic Dpt of Lab Med & Pathology
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 3 mL | Serum | SST (Gold) | Refrigerated |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 3 mL | Serum | No additive (Red) | Refrigerated |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 7 days |
| Refrigerated | 7 days |
| Frozen | 1 year |
Days Performed
1 day per week
Turnaround Time
5 - 19 days
Methodology
| Name | Description |
|---|---|
| Enzyme-Linked Immunosorbent Assay (ELISA) |
Reference Range
| Collagen Type II Antibody | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Negative: <20 EU/mL | Borderline/Equivocal: 20-25 EU/mL | Positive: >25 EU/mL |
Special Info
This test is New York State approved.
Clinical Info
Collagen II antibodies occur in 22% of patients with sensory neural hearing loss, 30% of patients with sudden deafness and 67% of patients with Meniere's disease. Collagen II antibodies also occur in patients with relapsing polychondritis and in patients with rheumatoid arthritis.