Complement Component C8




Test Mnemonic

COMPF8

CPT Codes

  • 86161 - QTY (1)

LOINC ®

50997-6

Aliases

  • (formerly Complement Functional C8)

Performing Laboratory

Mayo Clinic Dpt of Lab Med & Pathology


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mLSerumNo additive (Red) FrozenPatient should be fasting. Do not use serum separator tubes.

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.5 mL     

Stability

Environmental Condition Description
Frozen2 weeks
AmbientUnacceptable
RefrigeratedUnacceptable

Days Performed

Mon - Sat

Turnaround Time

2 - 4 days

Methodology

Name Description
Turbidimetry (TURB) 

Reference Range

Complement Component C8
Sex Age From Age To Type Range Range Unit
       Normal33 - 58U/mL

Special Info

Patient should be fasting. Do not use serum separator tubes.

Clinical Info

Low levels of complement may be due to inherited deficiencies, acquired deficiencies, or due to complement consumption (eg, as a consequence of infectious or autoimmune processes). Absent C8 levels in the presence of normal C3 and C4 values are consistent with a C8 deficiency. Absent C8 levels in the presence of low C3 and C4 values suggests complement consumption. Normal results indicate both normal C8 protein levels and normal functional activity. Absent (or low) C8 functional levels in the presence of normal C8 antigen levels should be replicated with a new serum specimen to confirm that C8 inactivation did not occur during shipping.