Cryptosporidium & Giardia Antigens by EIA
Test Mnemonic
OVAPSC
CPT Codes
- 87328 - QTY (1)
- 87329 - QTY (1)
LOINC ®
48059-0
Aliases
- Stool EIA
- Stool test
- STUL kit
- Stool kit
- Cryptosporidium Antigen
- Cryptosporidium EIA
- Giardia Antigen
- Giardia EIA
Includes
- Confirmation of all Cryptosporidium positive EIA, by microscopy with a modified acid-fast stain (CRYSPO). Additional charges for reflex testing apply.
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| Complete to fill line | Stool | C/S/Cary Blair | Refrigerated | Refrigerated | C&S/Cairy Blair and Ecofix available in a STUL kit; submit stool using a STUL kit at refrigerated conditions. STUL kit can be purchased via oracle #1570140. Refer to Stool collection guide (https://clevelandcliniclabs.com/our-laboratories/laboratory-medicine/microbiology/plmi-collection-guidelines-resources/stool-specimen-collection-guide/) |
| Complete to fill line | Stool | EcoFix fixative | Refrigerated | Refrigerated | C&S/Cairy Blair and Ecofix available in a STUL kit; submit stool using a STUL kit at refrigerated conditions. STUL kit can be purchased via oracle #1570140. Refer to Stool collection guide (https://clevelandcliniclabs.com/our-laboratories/laboratory-medicine/microbiology/plmi-collection-guidelines-resources/stool-specimen-collection-guide/) |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| Complete to fill line | Stool | C/S/Cary Blair | Refrigerated | Refrigerated | Reflex testing in-case of Cryptosporidium EIA positive will not be performed. Refer to Stool collection guide (https://clevelandcliniclabs.com/our-laboratories/laboratory-medicine/microbiology/plmi-collection-guidelines-resources/stool-specimen-collection-guide/) |
| 10 mL | Stool | Sterile container | Refrigerated | Refrigerated | Unpreserved stool should be submitted to the lab in a securely tightened sterile screw-top container and should be limited to inpatient settings due to a significantly shorter stability window. Use of non-standard (eg. food containers) is discouraged. Refer to Stool collection guide (https://clevelandcliniclabs.com/our-laboratories/laboratory-medicine/microbiology/plmi-collection-guidelines-resources/stool-specimen-collection-guide/) |
| Complete to fill line | Stool | Formalin 10% | Refrigerated | Refrigerated | |
| Complete to fill line | Stool | SAF | Refrigerated | Refrigerated |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 5 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | Preserved: 2 weeks Unpreserved: Preferred within 6 hours. Acceptable within 12 hours. |
| Refrigerated | Preserved: 2 weeks Unpreserved: Preferred within 6 hours. Acceptable within 12 hours. |
| Frozen | Preserved: 2 months Unpreserved: Unacceptable |
Days Performed
Mon - Fri
Turnaround Time
1 - 3 days
Methodology
| Name | Description |
|---|---|
| Enzyme Immunoassay (EIA) |
Reference Range
| Ova and Parasite Screen | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Negative for Giardia lamblia and Cryptosporidium species. |
Special Info
Recommend sending a complete STUL kit for submission of all outpatient specimens.
Clinical Info
Cryptosporidium and Giardia are the most common causes of parasitic intestinal disease. Acute disease is characterized by watery diarrhea, abdominal cramps etc. Cryptosporidium has also been implicated in several waterborne outbreaks. Chronic or asymptomatic infections can also occur. Prevalence of these parasites can vary among geographic areas and populations. A higher prevalence is seen in children and immunosuppressed population.
Clinical Limitation
Clinical correlation of assay results is suggested. Multiple specimens over several days can increase sensitivity of detection. Rapid immunochromatographic assays can generate false-positive results and confirmation with microscopy is recommended. Interfering substances include barium, bismuth, metamucil, castor oil, mineral oil, or antiamoebic drugs within one week prior to specimen collection can give false negative results. Excessively bloody and mucoid samples can yield false positive results.