CYP2C19 (Cytochrome P450 2C19)
Test Mnemonic
2C19CY
CPT Codes
- 81225 - QTY (1)
Aliases
- P450 2C19 Genotype
Includes
- EER CYP2C19
- CYP2C19 Genotype
- CYP2C19 Phenotype
- Interpretation
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 3 mL | Whole blood | EDTA (Lavender) | Refrigerated |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 3 mL | Whole blood | ACD A or B (Yellow) | Refrigerated | ||
| N/A | Saliva | See note | Ambient | Collect using Saliva Collection Device by DNA Genotek (OCD-100, ARUP supply #49295) |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Whole blood |
Stability
| Environmental Condition | Description |
|---|---|
| Refrigerated | Whole blood: 1 week; Saliva: Unacceptable |
| Ambient | Whole blood: 72 hours; Saliva: 2 weeks |
| Frozen | Whole blood: 1 month; Saliva: Unacceptable |
Days Performed
Varies
Turnaround Time
6 - 11 days
Methodology
| Name | Description |
|---|---|
| Fluorescence Monitoring | |
| Polymerase Chain Reaction (PCR) |
Special Info
Plasma, serum and frozen specimens in glass collection tubes will be rejected. Specimens collected in sodium heparin or lithium heparin are unacceptable. Whole blood is the preferred specimen. Saliva samples that yield inadequate DNA quality and/or quantity will be reported as inconclusive if test performance does not meet laboratory-determined criteria for reporting. This test is New York DOH approved.