Diphtheria Toxoid IgG Abs
Test Mnemonic
DIPIGG
CPT Codes
- 86317 - QTY (1)
LOINC ®
13227-4
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | SST (Gold) | Refrigerated | 'Pre' and 'post' vaccination specimens should be submitted together for testing. The 'post' specimen should be drawn 30 days after immunization. Label specimens clearly as 'Pre-Vaccine' or 'Post-Vaccine.' Separate serum from cells ASAP or within 2 hours of collection and transfer into a standard aliquot tube. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.15 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Refrigerated | After separation from cells: 2 weeks |
| Frozen | After separation from cells: 1 year (Avoid repeated freeze/thaw cycles) |
| Ambient | After separation from cells: 48 hours |
Days Performed
Sun - Sat
Turnaround Time
2 - 4 days
Methodology
| Name | Description |
|---|---|
| Quantitative Multiplex Bead Assay |
Reference Range
| Diphtheria IgG Abs | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| > 0.1 IU/mL is usually considered protective. |
Special Info
'Pre' and 'post' vaccination specimens should be submitted together for testing. 'Post' specimen should be drawn 30 days after immunization and, if shipped separately, must be received within 60 days of the 'pre' specimen. Clearly label specimens 'Pre-Vaccine' or 'Post-Vaccine.' Plasma or other body fluids will be rejected. This test is New York DOH approved.
Clinical Info
(1) If the post-vaccination is <1.0 IU/mL, the patient is considered a nonresponder. (2) If the post-vaccination concentration is greater than or equal to 1.0 IU/mL, a patient with a ratio of <1.5 is a nonresponder, a ratio of 1.5 to <3.0, is a weak responder, and a ratio of 3.0 or greater, is a good responder. (3) If the pre-vaccination concentration is >1.0 IU/mL, it may be difficult to assess the response based on a ratio alone. A post-vaccination concentration above 2.5 IU in this case is usually adequate.