Drug Detection Panel, TOF-MS, Umbilical Cord Tissue




Test Mnemonic

DRGTOF

CPT Codes

  • 80326 - QTY (1)
  • 80347 - QTY (1)
  • 80364 - QTY (1)
  • 80355 - QTY (1)

Includes

  • Buprenorphine
  • Norbuprenorphine
  • Codeine
  • Dihydrocodeine
  • Fentanyl
  • Hydrocodone
  • Norhydrocodone
  • Hydromorphone
  • Meperidine
  • Methadone
  • Methadone metabolite
  • 6-Acetylmorphine
  • Morphine
  • Naloxone
  • Oxycodone
  • Noroxycodone
  • Oxymorphone
  • Noroxymorphone
  • Propoxyphene
  • Tapentadol
  • Tramadol
  • N-desmethyltramadol
  • O-desmethyltramadol
  • Amphetamine
  • Benzoylecgonine
  • m-OH-Benzoylecgonine
  • Cocaethylene
  • Cocaine
  • MDMA-Ecstasy
  • Methamphetamine
  • Phentermine
  • Alprazolam
  • Alpha-OH-Alprazolam
  • Butalbital
  • Clonazepam
  • 7-Aminoclonazepam
  • Diazepam
  • Lorazepam
  • Midazolam
  • Alpha-OH-Midazolam
  • Nordiazepam
  • Oxazepam
  • Phenobarbital
  • Temazepam
  • Zolpidem
  • Phencyclidine - PCP
  • Gabapentin

Performing Laboratory

ARUP


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
Other Clean container RefrigeratedAt least 8 inches of umbilical cord (approximately the width of a sheet of paper). Drain and discard any blood. Rinse the exterior of the cord segment with normal saline or water. Pat the cord dry and transport at least 8 inches of umbilical cord in a routine urine collection cup or use the Security Kit for Meconium/Umbilical Drug Detection (ARUP supply #51548).

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
N/A    6 inches (Absolute minimum)

Stability

Environmental Condition Description
Refrigerated3 weeks
Frozen1 year
Ambient1 week

Days Performed

Sun - Sat

Turnaround Time

2 - 4 days

Methodology

Name Description
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) 

Reference Range

6-Acetylmorphine
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 1 ng/g 
7-Aminoclonazepam
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 1 ng/g 
Alpha-OH-Alprazolam
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 0.5 ng/g 
Alpha-OH-Midazolam
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 2 ng/g 
Alprazolam
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 0.5 ng/g 
Amphetamine
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 5 ng/g 
Benzoylecgonine
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 0.5 ng/g 
Buprenorphine
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 1 ng/g 
Butalbital
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 25 ng/g 
Clonazepam
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 1 ng/g 
Cocaethylene
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 1 ng/g 
Cocaine
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 0.5 ng/g 
Codeine
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 0.5 ng/g 
Diazepam
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 1 ng/g 
Dihydrocodeine
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 1 ng/g 
EDDP
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 1 ng/g 
Gabapentin
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 10 ng/g 
Hydrocodone
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 0.5 ng/g 
Hydromorphone
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 0.5 ng/g 
Lorazepam
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 5 ng/g 
MDMA- Ecstasy
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 5 ng/g 
Meperidine
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 2 ng/g 
Methadone
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 2 ng/g 
Methamphetamine
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 5 ng/g 
Midazolam
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 1 ng/g 
m-OH-Benzoylecgonine
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 1 ng/g 
Morphine
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 0.5 ng/g 
Naloxone
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 1 ng/g 
N-desmethyltramadol
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 2 ng/g 
Norbuprenorphine
Sex Age From Age To Type Range Range Unit
       Normalcutoff 0.5 ng/g 
Nordiazepam
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 1 ng/g 
Norhydrocodone
Sex Age From Age To Type Range Range Unit
       Normalcutoff 1 ng/g 
Noroxycodone
Sex Age From Age To Type Range Range Unit
       Normalcutoff 1 ng/g 
Noroxymorphone
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 0.5 ng/g 
O-desmethyltramadol
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 2 ng/g 
Oxazepam
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 2 ng/g 
Oxycodone
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 0.5 ng/g 
Oxymorphone
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 0.5 ng/g 
Phencyclidine-PCP
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 1 ng/g 
Phenobarbital
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 75 ng/g 
Phentermine
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 8 ng/g 
Propoxyphene
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 1 ng/g 
Tapentadol
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 2 ng/g 
Temazepam
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 1 ng/g 
Tramadol
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 2 ng/g 
Zolpidem
Sex Age From Age To Type Range Range Unit
       Freetextcutoff 0.5 ng/g 

Special Info

Cords soaking in blood or other fluids are unacceptable. Formalin-fixed specimens or tissue that is obviously decomposed will not be accepted. This test is New York DOH approved.

Clinical Info

Detection of drugs in umbilical cord tissue is intended to reflect maternal drug use during approximately the last trimester of a full-term pregnancy. The pattern and frequency of drug(s) used by the mother cannot be determined by this test. A negative result does not exclude the possibility that a mother used drugs during pregnancy. Detection of drugs in umbilical cord tissue depends on extent of maternal drug use, as well as drug stability, unique characteristics of drug deposition in umbilical cord tissue, and the performance of the analytical method. Drugs administered during labor and delivery may be detected. Detection of drugs in umbilical cord tissue does not insinuate impairment and may not affect outcomes for the infant. Interpretive questions should be directed to the laboratory.