Expanded Respiratory Pathogen Panel by PCR (with COVID), Routine




Test Mnemonic

RPPCR

CPT Codes

  • 0202U - QTY (1)

Aliases

  • Respiratory Viral panel
  • RVP
  • resp pathogen
  • resp viral panel
  • resp virus
  • respiratory virus

Includes

  • SARS-CoV-2
  • Human Rhinovirus/Enterovirus
  • Influenza A virus
  • Influenza A virus A/H1
  • Influenza A virus A/H3
  • Influenza A virus A/H1-2009
  • Influenza B virus
  • Respiratory syncytial virus
  • Bordetella parapertussis
  • Bordetella pertussis
  • Chlamydia pneumoniae
  • Human Metapneumovirus
  • Adenovirus
  • Parainfluenza virus 1
  • Parainfluenza virus 2
  • Parainfluenza virus 3
  • Parainfluenza virus 4
  • Coronavirus 229E
  • Coronavirus OC43
  • Coronavirus NL63
  • Coronavirus HKU1
  • Mycoplasma pneumoniae

Performing Laboratory

Cleveland Clinic Laboratories


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
OneNasopharyngeal swabSwab RefrigeratedUTM, VTM, or saline is acceptable.

Alternate Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mLBronch (BAL)Sterile container RefrigeratedIf aliquotting is necessary, Sterile aliquot tubes must be used. Do not dilute with UTM or VTM
OneSputum, inducedSterile container RefrigeratedIf aliquotting is necessary, Sterile aliquot tubes must be used. Do not dilute with UTM or VTM

Stability

Environmental Condition Description
RefrigeratedNasopharyngeal Swab: Stable for 3 days at 2-8°C Lower Respiratory Samples (BAL, induced sputum): Stable for 7 days at 2-8°C
FrozenNasopharyngeal Swab: Stable for 30 days at -70°C Lower Respiratory Samples (BAL, induced sputum): Stable for 30 days at -70°C
AmbientNasopharyngeal Swab: Stable for 4 hours at 15-25°C. Lower Respiratory Samples (BAL, induced sputum): Not acceptable.

Days Performed

Sun - Sat

Turnaround Time

2 - 3 days

Methodology

Name Description
Multiplex 
Qualitiative Real-Time PCR 

Reference Range

COVID 19 Result NP
Sex Age From Age To Type Range Range Unit
       Negative for COVID19 (SARS CoV2) by RT-PCR or equivalent method. 

Special Info

Dry swabs (swabs not received in viral transport media) will be rejected. Lower respiratory specimens received in universal transport media or viral transport media will be rejected. Test is not performed on Cleveland Clinic Holidays.

Clinical Info

This test is for immunocompromised patients, severely ill adults who will be hospitalized and have evidence of a lower respiratory tract infection the etiology of which has not been determined, and children who are going to be admitted that are being evaluated for a suspected respiratory viral infection. Note: This test (the Respiratory Panel) should rarely be ordered in the outpatient setting, and if ordered, preauthorization should be strongly considered. The test is very expensive and if not covered by insurance the patient will incur a substantial charge.