FISH for DUSP22-IRF4 Tissue

Test Mnemonic


CPT Codes

  • 88377 - QTY (1)


  • FISH for 6p25

Performing Laboratory

Cleveland Clinic Laboratories

Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
2 slidesParaffin block, formalin fixedSlides, unstainedAmbient One formalin-fixed, paraffin embedded block containing representative tissue OR unstained 4 μm tissue sections on electrostatically charged slides containing representative tumor. Tissue must be fixed in formalin NOT B5 or PREFER fixative


Environmental Condition Description
AmbientFFPE slides at room temperature

Days Performed

5 days per week

Turnaround Time

3 - 5 days


Name Description
Fluorescent In-Situ Hybridization (FISH) 

Clinical Info

Interphase FISH analysis utilizing a dual color, break-apart probe for the DUSP22/IRF4 genes at 6p25.3. Rearrangements involving these genes are observed in ALK-negative, anaplastic large cell lymphomas. The translocation partner cannot be identified in this assay. If no cells are available for analysis, no analysis charges will be incurred.