FISH for FOXO1A gene (13q14)(FKHR)
Test Mnemonic
FKHR
CPT Codes
- 88377 - QTY (1)
Aliases
- FISH for FKHR gene (13q14)
- Fluorescence In Situ Hybridization for FKHR (13q14)
Includes
- LSI 13q14
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 2 slides | Slide (s), unstained | Clean container | Ambient | Ambient | One formalin-fixed, paraffin embedded block containing representative tissue OR unstained 4 μm tissue sections on electrostatically charged slides containing representative tumor. Tissue must be fixed in formalin NOT B5 or PREFER fixative |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | FFPE tissue blocks and slides from FFPE specimens are stable at ambient temperatures |
Days Performed
5 days per week
Turnaround Time
5 - 7 days
Methodology
| Name | Description |
|---|---|
| Fluorescent In-Situ Hybridization (FISH) |
Clinical Info
Interphase FISH analysis utilizing a dual color, break-apart probe for the FOXO1A gene at 13q14.11. Rearrangements involving the FOXO1A gene are observed in alveolar rhabdomyosarcoma. The translocation partner gene cannot be identified in this assay. If no cells are available for analysis, no analysis charges will be incurred.