FISH for HER-2
Test Mnemonic
HER2F
CPT Codes
- 88377 - QTY (1)
Aliases
- Breast Cancer (HER2) Gene Amplification
- FISH for HER2 Breast
- Her-2 Neu
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| N/A | Tissue, formalin fixed | Clean container | Ambient | Breast cancer tissue. IHC data must be included when ordering HER2 FISH testing. | |
| N/A | Slide (s), unstained | Clean container | N/A | Ambient | 4 um tissue sections on positively charged slides. Samples must not be fixed in Prefer or B5. IHC data must be included when ordering HER2 FISH testing. |
Days Performed
Mon - Thu
Turnaround Time
5 - 7 days
Methodology
| Name | Description |
|---|---|
| Fluorescent In-Situ Hybridization (FISH) |
Reference Range
Special Info
Breast cancer tissue. IHC data must be included when ordering HER2 FISH testing. 4 um tissue sections on positively charged slides. Samples must not be fixed in Prefer or B5. IHC data must be included when ordering HER2 FISH testing.
Clinical Info
Determination of gene amplification and over expression for the oncogene Her - 2 - neu in breast carcinoma. Results reported as gene amplification present (amplified/positive) or absent (not amplified/negative). Gene copy number is specified.