FISH for IgH/BCL2 Blood
Test Mnemonic
FSHFCL
CPT Codes
- 88271 - QTY (2)
- 88275 - QTY (1)
- 88291 - QTY (1)
- 88237 - QTY (1)
Aliases
- FISH for t(14;18) translocation
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 5 - 7 mL | Blood, peripheral | EDTA (Lavender) | Ambient | Ambient | Specimens which will not be processed by the performing laboratory within 72 hours of draw are considered unsatisfactory. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 5 - 7 mL | Blood, peripheral | Sodium heparin (Green) | Ambient | Ambient | Specimens which will not be processed by the performing laboratory within 72 hours of draw are considered unsatisfactory. |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 48 hours |
| Refrigerated | Acceptable |
| Frozen | Not acceptable |
Days Performed
5 days per week
Turnaround Time
3 - 5 days
Methodology
| Name | Description |
|---|---|
| Fluorescent In-Situ Hybridization (FISH) |
Clinical Info
This assay uses a dual color, dual fusion probe to detect the IGH/BCL2 translocation that is associated with follicular lymphoma and diffuse large B-cell lymphoma. This test should not be used to monitor minimal residual disease.