FISH for IGH/CCND1 Tissue

Test Mnemonic


CPT Codes

  • 88377 - QTY (2)


  • FISH for t(11;14)


  • LSI 11q13.3
  • LSI 14q32.33

Performing Laboratory

Cleveland Clinic Laboratories

Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
2 slidesSlide (s), unstained AmbientAmbient4 μm tissue sections on electrostatically charged slides containing representative tumor. Tissue must be formalin fixed. Samples must not be fixed in B5 or Prefer fixative.


Environmental Condition Description
AmbientBlocks and slides should be transported at ambient temperature

Days Performed

5 days per week

Turnaround Time

3 - 5 days


Name Description
Fluorescent In-Situ Hybridization (FISH) 

Clinical Info

Interphase FISH analysis utilizing a dual color, dual fusion probe set specific to the CCND1 gene at 11q13.3 and the IGH gene at 14q32.33. This is useful in distinguishing patients with the t(11;14) translocation. If no cells are available for analysis, no analysis charges will be incurred.