FISH for IGH/MYC/CEP8 Tissue




Test Mnemonic

T814

CPT Codes

  • 88377 - QTY (1)

Aliases

  • FISH for t(8;14)

Includes

  • LSI 8q24.1
  • LSI 14q32.33

Performing Laboratory

n/a


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
2 slidesSlide (s), unstainedClean container Ambient4 μm tissue sections on electrostatically charged slides. Tissue must be formalin fixed. Samples must not be fixed in Prefer or B5.

Stability

Environmental Condition Description
AmbientBlocks and slides should be transported at ambient temperature.

Days Performed

5 days per week

Turnaround Time

3 - 5 days

Methodology

Name Description
Fluorescent In-Situ Hybridization (FISH) 

Clinical Info

Interphase FISH analysis utilizing a three color, dual fusion probe set specific to the MYC gene at 8q24.1 and the IGH gene at 14q32.33, in conjunction with the centromere of chromosomes 8. The t(8;14) rearrangement may be seen in Burkitt lymphoma and double hit B-cell lymphomas. If no cells are available for analysis, no analysis charges will be incurred.