FISH for SYT gene (18q11)

Test Mnemonic


CPT Codes

  • 88377 - QTY (1)


  • Fluorescence In Situ Hybridization for SYT gene(18q11)


  • LSI 18q11

Performing Laboratory

Cleveland Clinic Laboratories

Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
2 slidesSlide (s), unstainedClean container Ambient4 um tissue sections on electrostatically charged slides. Samples must not be fixed in Prefer or B5.


Environmental Condition Description
AmbientFFPE blocks and slides

Days Performed

5 days per week

Turnaround Time

5 - 7 days


Name Description
Fluorescent In-Situ Hybridization (FISH) 

Clinical Info

Interphase FISH analysis utilizing a dual color, break-apart probe for the SS18 (SYT) gene at 18q11.2. Rearrangements of the SS18 gene are observed in synovial sarcoma. The translocation partner gene cannot be identified with this assay. If no cells are available for analysis, no analysis charges will be incurred.