Head and Neck Next Generation Sequencing

Test Mnemonic


CPT Codes

  • 81445 - QTY (1)

Performing Laboratory

Cleveland Clinic Laboratories

Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
10 mm squareBlock, Formalin fixed paraffinSlidesAmbient Formalin-fixed paraffin-embedded tissue slides. Transport and store slides at ambient temperature. 10 unstained sections FFPE tissue on charged, unbaked slides plus one H&E stained section with best tumor area circled by a pathologist.


Environmental Condition Description
AmbientIndefinitely for FFPET slides. FFPET slides are transported at ambient temperature.
FrozenNot acceptable.
RefrigeratedNot acceptable.

Days Performed

Once per week

Turnaround Time

14 days


Name Description
Next Gen Sequencing 

Special Info

The following genes are interrogated: ALK, BRAF, CAMTA1, CRTC1, ETV6, EWSR1, FOS, FOSB. FOXO1, FUS, GLI1, HMGA2, MAML2, MKL2, MYB, NCOA1, NR4A3, NTRK1, NTRK2, NTRK3, NUTM1, PAX3, PAX7, PLAG1, PRKD1, RET, SS18, STAT6, TFE3, AND YAP1.