Hepatitis B Surface Ab




Test Mnemonic

AHBSAG

CPT Codes

  • 86706 - QTY (1)

LOINC ®

22322-2

Aliases

  • HBsAb

Performing Laboratory

Cleveland Clinic Laboratories


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.5 mLSerumSST (Gold) Refrigerated 

Alternate Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.5 mLPlasmaEDTA (Lavender)   

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.25 mL     

Stability

Environmental Condition Description
Ambient3 days
Frozen14 days
Refrigerated7 days

Days Performed

Sun - Sat

Turnaround Time

1 - 3 days

Methodology

Name Description
Chemiluminescent Microparticle Immunoassay (CMIA) 

Reference Range

Hepatitis B Surface Ab, Quant
Sex Age From Age To Type Range Range Unit
       Freetext<8.00 mIU/mL: Negative; 8.00-11.99 mIU/mL: Equivocal; > or = to 12.00 mIU/mL: Positive 

Special Info

A non-reactive test result does not exclude the possibility of exposure to hepatitis B virus. Assay does not differentiate Hepatitis B surface antibody from vaccination and or natural infection.

Clinical Info

To assess adequacy of recent or remote immune response to HBV infection or vaccination. Negative values: No evidence of antibodies to Hepatitis B surface antigen. Equivocal values: Indeterminate result. In patients who were vaccinated 6-8 weeks prior to this draw or previously infected with HBV, repeat testing is suggested. Those who were vaccinated for Hepatitis B virus years ago, may fall into this category due to waning immunity over time. Clinical correlation is required. Positive values: These results are consistent with immunity to the hepatitis B virus due to previous exposure to Hepatitis B virus or Hepatitis B vaccination.

Clinical Limitation

Test is not intended for use in screening blood, plasma, or tissue donors. Performance characteristics have not been established for immunocompromised patients. Performance has not been established for the use of cadaveric specimens. Criteria for Rejection: Heat-inactivated, pooled, grossly hemolyzed, obvious microbial contamination.