Hexosaminidase A & Total, WBC
Test Mnemonic
TAYSAC
CPT Codes
- 83080 - QTY (2)
LOINC ®
24075-4
Aliases
- Tay Sachs Disease
- Hexosaminidase Total
Includes
- Total Hexosaminidase
- Hexosaminidase A
Performing Laboratory
Mayo Clinic Dpt of Lab Med & Pathology
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 6 mL | Whole blood | ACD A or B (Yellow) | Refrigerated | Collect Monday - Wednesday only. Deliver to Cleveland Clinic Laboratories by 3 p.m. on the day of collection. Do not collect the day before a holiday. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 5 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Refrigerated | 4 days |
| Ambient | 4 days |
| Frozen | Unacceptable |
Days Performed
Mon, Thu, Fri
Turnaround Time
5 - 9 days
Methodology
| Name | Description |
|---|---|
| Heat inactivation | |
| Fluorometry (FLM) |
Reference Range
| Hexosaminidase A | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 15 Years | Normal | 20-80 | % of total | 16 Years | 99 Years | Normal | 63-75 | % of total |
| Total Hexosamin | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 15 Years | Normal | >=20 | nmol/min/mg | 16 Years | 99 Years | Normal | 16.4-36.2 | nmol/min/mg |
Special Info
Informed consent is required for patients residing in New York state.
Clinical Info
Useful for Tay-Sachs disease and carriers of Tay-Sachs and also for Sandhoff's disease and carriers of Sandhoff's.