Histoplasma galactomannan Antigen, Urine
Test Mnemonic
UHISTO
CPT Codes
- 87385 - QTY (1)
LOINC ®
44524-7
Aliases
- Histoplasma capsulatum Ag
- Histoplasma galactomannan Ag
- Histo
- Histoplasma polysaccharide
Includes
- Histoplasma Ag
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Urine, random | Sterile container | Refrigerated |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 2 days |
| Refrigerated | 2 weeks |
| Frozen | 60 days |
Days Performed
Tue, Fri
Turnaround Time
1 - 5 days
Methodology
| Name | Description |
|---|---|
| Enzyme Immunoassay (EIA) |
Reference Range
| Histoplasma Antigen | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | Negative | ||||
| Urine Histoplasma Ag Quantitative | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | < 0.20 | ng/mL |
Clinical Info
Histoplasma galactomannan antigen, urine test is used as an aid in diagnosing histoplasmosis. A negative result cannot rule out infection. Low positive results may at times be due to cross-reactivity with Blastomyces, Talaromyces marneffei, Paracoccidioides, Aspergillus spp., and some Candida species. Clinical, radiological, and epidemiological correlation is required.
Clinical Limitation
The performance of this test is unknown when urine specimens including the following substances are tested: foods which produce color in urine, vaginal cream, caffeine, ascorbic acid, itraconazole, amphotericin B, acetaminophen, or acetylsalicylic acid. Results between different Histoplasma assays cannot be compared.