HIV Phenotype
Test Mnemonic
HIVPHE
CPT Codes
- 87903 - QTY (1)
- 87904 - QTY (12)
Aliases
- HIV Phenotypic Resistance Testing
- PhenoSense HIV Comprehensive
Includes
- All approved HIV antiretroviral drugs
- Viral replication capacity
Performing Laboratory
LabCorp
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 3 mL | Plasma | EDTA PPT (White) | Frozen | Collect two EDTA PPT White tubes and centrifuge within 6 hours of collection. Transfer plasma to one or more screw-cap tubes and freeze immediately. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 3 mL | Plasma | EDTA (Lavender) | Frozen | Collect two EDTA Lavender tubes and centrifuge within 6 hours of collection. Transfer plasma to one or more screw-cap tubes and freeze immediately. Clearly indicate "EDTA Plasma" on the specimen label. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 6 hours |
| Refrigerated | 24 hours |
| Frozen | 2 weeks (avoid freeze/thaw cycles) |
Days Performed
Sun - Sat
Turnaround Time
16 - 23 days
Methodology
| Name | Description |
|---|---|
| Reverse Transcription/Polymerase Chain Reaction (RT/PCR) | |
| Transfection, Luciferase Activity |
Reference Range
Special Info
Assay is intended for use ONLY for patient's with viral loads greater than or equal to 500 copies/mL.
Clinical Info
Direct quantitative measurement of how well a patient's virus responds to antiretrovirals. Report includes drug resistance information for all approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucleoside reverse transcriptase inhibitors (NNRTIs), and protease inhibitors (PIs), as well as a measure of replication capacity which can provide treatment insight.