Hypercoagulation Diagnostic Interpretive Panel | Cleveland Clinic Laboratories

Hypercoagulation Diagnostic Interpretive Panel Print

Test Mnemonic

HYPER

CPT Codes

86147 - QTY (3)
83090 - QTY (1)
85610 - QTY (1)
85730 - QTY (1)
85384 - QTY (1)
85303 - QTY (1)
86140 - QTY (1)
81240 - QTY (1)
85390 - QTY (1)
85670 - QTY (1)
85520 - QTY (1)
85730 - QTY (1)

Aliases

Hypercoagulation Panel

Performing Laboratory

Cleveland Clinic Laboratories

Specimen Requirements

Volume	Type	Container	Transport Temperature	Special Instructions
2 mL	Serum	SST (Gold)	Frozen	Indicate clearly which tube is plasma and which tube is serum. Submit Coagulation Consultation Patient History Form.
4 mL	Whole blood	EDTA (Lavender)	Refrigerated
6 mL	Plasma	Sodium citrate (Lt. Blue)	Frozen

Minimum Specimen Requirements

Volume	Type	Container	Collect Temperature	Transport Temperature	Special Instructions
2 mL					Whole blood EDTA (Lavender)
1 mL					Serum
3 mL					Citrated plasma

Stability

Environmental Condition	Description
Ambient	4 hours
Frozen	14 days at -20 C; 6 months at -70 C
Refrigerated	Unacceptable

Days Performed

Mon - Fri

Turnaround Time

3 - 5 days

Methodology

Name	Description
Refer to individual components

Reference Range

APTT Screen
Sex	Age From	Age To	Type	Range	Range Unit
	Days	1 Days	Normal	28.2-47.4	sec
	1 Months	3 Months	Normal	21.7-43.5	sec
	2 Days	5 Days	Normal	22.9-52.0	sec
	6 Days	30 Days	Normal	23.1-48.0	sec
	4 Months	11 Months	Normal	25.3-37.3	sec
	1 Years	5 Years	Normal	21.3-31.6	sec
	6 Years	10 Years	Normal	23.1-31.6	sec
	11 Years	16 Years	Normal	23.1-32.5	sec
	17 Years	99 Years	Normal	24.0-35.1	sec
Thrombin Time
Sex	Age From	Age To	Type	Range	Range Unit
	Days	1 Days	Normal	< 17.3	sec
	2 Days	5 Days	Normal	< 17.9	sec
	6 Days	30 Days	Normal	< 17.9	sec
	1 Months	3 Months	Normal	< 18.2	sec
	4 Months	11 Months	Normal	< 19.1	sec
	1 Years	999 Years	Normal	< 18.6	sec

Special Info

Patient Preparation: Discontinue coumadin therapy for 7 days, heparin therapy for 2 days and thrombolytic therapy for 7 days prior to test, if possible. 3.2% sodium citrate is the preferred anticoagulant recommended by CLSI. Per Pathologist review, the following tests may be ordered and billed: ATIII functional(85300); ATIII Antigen (85301); Protein S clottable (85306), APCR (85307); PTT Incubated Mixing Add On (85730, 85732 x2); Dilute Russell Viper Venom (85613); Staclot (85730, 85732); Platelet Neutralization (85597); Factor V Leiden (81241); MTHFR by PCR (81291); Reptilase (85635); Fibrinogen Antigen (85385); D-Dimer (85379); Prot C Immunologic (85302); Prot S Immunologic (85306); Factor VIII clotting or chromogenic (85240); Sample must be accompanied by the completed Clinical History Form for Hemostasis and Thrombosis Evaluation and a medication list.

Clinical Info

Use in the evaluation of congenital or acquired disorders associated with a hypercoagulable state.