Hypercoagulation Diagnostic Interpretive Panel




Test Mnemonic

HYPER

CPT Codes

  • 86147 - QTY (3)
  • 83090 - QTY (1)
  • 85610 - QTY (1)
  • 85730 - QTY (1)
  • 85384 - QTY (1)
  • 85303 - QTY (1)
  • 86140 - QTY (1)
  • 81240 - QTY (1)
  • 85390 - QTY (1)
  • 85670 - QTY (1)
  • 85520 - QTY (1)
  • 85730 - QTY (1)

Aliases

  • Hypercoagulation Panel

Performing Laboratory

Cleveland Clinic Laboratories


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
2 mLSerumSST (Gold) FrozenIndicate clearly which tube is plasma and which tube is serum. Submit Coagulation Consultation Patient History Form.
4 mLWhole bloodEDTA (Lavender) Refrigerated 
6 mLPlasmaSodium citrate (Lt. Blue) Frozen 

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
2 mL    Whole blood EDTA (Lavender)
1 mL    Serum
3 mL    Citrated plasma

Stability

Environmental Condition Description
Ambient4 hours
Frozen14 days at -20 C; 6 months at -70 C
RefrigeratedUnacceptable

Days Performed

Mon - Fri

Turnaround Time

3 - 5 days

Methodology

Name Description
Refer to individual components 

Reference Range

APTT Screen
Sex Age From Age To Type Range Range Unit
   Days1 DaysNormal28.2-47.4sec
 1 Months3 MonthsNormal21.7-43.5sec
 2 Days5 DaysNormal22.9-52.0sec
 6 Days30 DaysNormal23.1-48.0sec
 4 Months11 MonthsNormal25.3-37.3sec
 1 Years5 YearsNormal21.3-31.6sec
 6 Years10 YearsNormal23.1-31.6sec
 11 Years16 YearsNormal23.1-32.5sec
 17 Years99 YearsNormal24.0-35.1sec
Thrombin Time
Sex Age From Age To Type Range Range Unit
   Days1 DaysNormal< 17.3sec
 2 Days5 DaysNormal< 17.9sec
 6 Days30 DaysNormal< 17.9sec
 1 Months3 MonthsNormal< 18.2sec
 4 Months11 MonthsNormal< 19.1sec
 1 Years999 YearsNormal< 18.6sec

Special Info

Patient Preparation: Discontinue coumadin therapy for 7 days, heparin therapy for 2 days and thrombolytic therapy for 7 days prior to test, if possible. 3.2% sodium citrate is the preferred anticoagulant recommended by CLSI. Per Pathologist review, the following tests may be ordered and billed: ATIII functional(85300); ATIII Antigen (85301); Protein S clottable (85306), APCR (85307); PTT Incubated Mixing Add On (85730, 85732 x2); Dilute Russell Viper Venom (85613); Staclot (85730, 85732); Platelet Neutralization (85597); Factor V Leiden (81241); MTHFR by PCR (81291); Reptilase (85635); Fibrinogen Antigen (85385); D-Dimer (85379); Prot C Immunologic (85302); Prot S Immunologic (85306); Factor VIII clotting or chromogenic (85240); Sample must be accompanied by the completed Clinical History Form for Hemostasis and Thrombosis Evaluation and a medication list.

Clinical Info

Use in the evaluation of congenital or acquired disorders associated with a hypercoagulable state.