IgVH Mutation Analysis
Test Mnemonic
IGVH
CPT Codes
- 81263 - QTY (1)
Aliases
- IgVH Somatic Hypermutation
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 5 mL | Whole blood | EDTA (Lavender) | Refrigerated | Please collect 2 lavender top tubes. Specimen MUST be sent to Cleveland Clinic Laboratories on the day of collection. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 3 mL | Bone marrow | EDTA (Lavender) | Refrigerated | Specimen MUST be sent to Cleveland Clinic Laboratories on the day of collection. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | EDTA Whole Blood or Bone Marrow |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 1 hour |
| Refrigerated | 2 days |
| Frozen | Unacceptable |
Days Performed
Varies
Turnaround Time
9 - 13 days
Methodology
| Name | Description |
|---|---|
| Polymerase Chain Reaction (PCR) | |
| Sequencing |
Reference Range
Special Info
This assay is designed for individuals with a confirmed diagnosis of CLL, and for these individuals testing will include sequencing at an additional cost. All other diagnoses will terminate after amplification and will not have the sequencing component. Refrigerated specimens should be received at the performing lab within 48 hours of collection for optimal viability. This test is New York DOH approved.