Islet antigen-2 antibody
Test Mnemonic
IA2AB
CPT Codes
- 86341 - QTY (1)
Aliases
- Anti-IA2 antibodies
- IA-2 antibody
- Insulinoma-associated antibody 2
- Islet antigen-2 antibody
- Islet cell antigen antibody
- Tyrosine phosphatase-related islet antigen 2 antibody
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL | Serum | SST (Gold) | Frozen |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.1 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 24 hours |
| Refrigerated | 14 days |
| Frozen | 14 days |
Days Performed
Wed
Turnaround Time
1 - 8 days
Methodology
| Name | Description |
|---|---|
| Enzyme-Linked Immunosorbent Assay (ELISA) |
Reference Range
| Insulinoma Associated Antibody 2 | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | <7.5 | U/mL |
Special Info
The test is not to be used alone and is to be used in conjunction with other clinical and laboratory findings.
Clinical Info
Anti-insulinoma associated antigen 2 (IA-2) antibody test is used as an aid in diagnosis of type I diabetes mellitus, to predict the risk of progression to type I diabetes mellitus among susceptible individuals, and to predict the necessity of insulin therapy in adult-onset diabetes mellitus. Clinical correlation is required.
Clinical Limitation
Plasma is unacceptable. Lipemic and grossly hemolyzed samples should not be tested. Visibly turbid samples will have interference with this assay.