Lambda, Free, Serum
Test Mnemonic
FLAMBS
CPT Codes
- 83521 - QTY (1)
LOINC ®
33944-0
Aliases
- Free Lambda Light Chains
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | SST (Gold) | Refrigerated |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 24 hours |
| Refrigerated | 21 days |
| Frozen | 30 days |
Days Performed
Mon - Fri
Turnaround Time
1 - 4 days
Methodology
| Name | Description |
|---|---|
| Turbidimetry (TURB) |
Reference Range
| Lambda, Free, Serum | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | 5.7 - 26.3 | mg/L |
Special Info
The Lambda Free Light Chain was performed using the Binding Site Optilite immunoturbidimetric method. Result obtained with different assay methods or kits cannot be used interchangeably.
Clinical Info
Elevated serum levels of monoclonal free light chains are associated with malignant plasma cell proliferation (eg. multiple myeloma), AL amyloidosis, and light chain deposition disease. Raised serum levels of polyclonal free light chains may be associated with autoimmune OR chronic infectious diseases.
Clinical Limitation
This assay has not been validated for the pediatric population.