LPT to Beryllium, Blood




Test Mnemonic

BLDBE

CPT Codes

  • 86353 - QTY (1)

Performing Laboratory

Cleveland Clinic Laboratories


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
30 mLWhole bloodSodium heparin (Green) AmbientCollect Monday - Thursday only. Deliver the specimen to the lab within 48 hours post collection. Do not aliquot. Specimen must remain at ambient temperature. Do not refrigerate. Do not freeze. Collect sample in a sterile container using aseptic technique. Sample cannot be shared with other testing. This test cannot be added on to other testing.

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
20 mL     

Stability

Environmental Condition Description
Ambient48 hours
RefrigeratedUnacceptable
FrozenUnacceptable

Days Performed

Mon - Fri

Turnaround Time

10 - 14 days

Methodology

Name Description
Radioactive thymidine uptake in cell culture 

Reference Range

Beryllium 1.0 uM D5
Sex Age From Age To Type Range Range Unit
       Normal< 3.0SI
Beryllium 1.0 uM D6
Sex Age From Age To Type Range Range Unit
       Normal< 3.0SI
Beryllium 10 uM D5
Sex Age From Age To Type Range Range Unit
       Normal< 3.0SI
Beryllium 10 uM D6
Sex Age From Age To Type Range Range Unit
       Normal< 3.0SI
Beryllium 100 uM D5
Sex Age From Age To Type Range Range Unit
       Normal< 3.0SI
Candida Albicans
Sex Age From Age To Type Range Range Unit
       Normal> 2.0SI
PHA Stimulation Index
Sex Age From Age To Type Range Range Unit
       Normal> 50.0SI

Special Info

Contact testing laboratory prior to collecting specimen at (216) 444-2502. Specimens should not be collected or delivered on weekends or holidays. Contact testing lab prior to collecting the specimens.

Clinical Info

Lymphocyte proliferation test to Beryllium is a cellular assay used as an aid in diagnosis of prior sensitization to Beryllium in the environment. Beryllium-sensitized individuals may remain asymptomatic for extended periods and never develop chronic berylliosis. Clinical, epidemiological, and radiological correlation is required. Bronchoalveolar lavage testing may offer higher sensitivity than whole blood testing where pulmonary disease is suspected.