MAG Antibodies, IgM and SGPG Antibodies, IgM




Test Mnemonic

MASGPG

CPT Codes

  • 83516 - QTY (2)

Aliases

  • Myelin Associated Glycoprotein Abs,
  • IgM & Sulfate-3-Glucuronyl Paragloboside Abs, IgM

Performing Laboratory

ARUP


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.5 mLSerumSST (Gold) RefrigeratedSeparate serum from cells ASAP or within 2 hours of collection

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.1 mL    Separate serum from cells ASAP or within 2 hours of collection

Stability

Environmental Condition Description
AmbientAfter separation from cells: 2 days
RefrigeratedAfter separation from cells: 2 weeks
FrozenAfter separation from cells: 1 year

Days Performed

Tue

Turnaround Time

2 - 9 days

Methodology

Name Description
Enzyme-Linked Immunosorbent Assay (ELISA) 

Reference Range

Myelin Associated Glycoprotein (MAG) Ab, IgM
Sex Age From Age To Type Range Range Unit
       MAG Antibody, IgM: < 1000 Titer Units 
SGPG Antibody, IgM
Sex Age From Age To Type Range Range Unit
       SGPG Antibody, IgM: < 1.00 IV 

Special Info

Separate serum from cells ASAP or within 2 hours of collection.

Clinical Info

Detection of IgM antibody against myelin-associated glycoprotein(MAG) suggests active demyelination in peripheral neuropathy. The possiblity of MAG antibody involvement in a suspected neropathy may essentially be ruled out if a MAG IgM negative result is obtained. The majority of sulfate-3-glucuronyl paragloboside(SPGP) IgM positive sera will show reactivity against MAG. Patients who are SGPG IgM positive and MAG IgM negative may have multi-focal motor neuropathy with conduction block.

Clinical Limitation

n/a

Clinical Reference

n/a