Methylmalonic Acid Blood | Cleveland Clinic Laboratories

Methylmalonic Acid Blood Print

Test Mnemonic

MMA

CPT Codes

83921 - QTY (1)

LOINC ^®

13964-2

Aliases

MMA, Blood

Performing Laboratory

Cleveland Clinic Laboratories

Specimen Requirements

Volume	Type	Container	Collect Temperature	Transport Temperature	Special Instructions
2 mL	Plasma	Lithium heparin PST (Lt. Green)		Refrigerated	Centrifuge and transfer plasma to a clean, tightly sealed tube within 2 hours of collection. Refrigerate within 24 hours.

Alternate Specimen Requirements

Volume	Type	Container	Collect Temperature	Transport Temperature	Special Instructions
2 mL	Plasma	Sodium heparin (Green)		Refrigerated	Centrifuge and transfer plasma to a clean, tightly sealed tube within 2 hours of collection. Refrigerate within 24 hours.
2 mL	Serum	No additive (Red)		Refrigerated	Centrifuge and transfer serum to a clean, tightly sealed tube within 2 hours of collection. Refrigerate within 24 hours.
2 mL	Serum	SST (Gold)		Refrigerated	Centrifuge and transfer serum to a clean, tightly sealed tube within 2 hours of collection. Refrigerate within 24 hours.

Minimum Specimen Requirements

Volume	Type	Container	Collect Temperature	Transport Temperature	Special Instructions
0.7 mL

Stability

Environmental Condition	Description
Ambient	48 Hours
Refrigerated	14 Days
Frozen	6 Months

Days Performed

Mon - Fri

Turnaround Time

1 - 6 days

Methodology

Name	Description
High Performance Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

Reference Range

Methylmalonic Acid Blood
Sex	Age From	Age To	Type	Range	Range Unit
	Years	99 Years	Normal	<= 0.40	umol/L
	Years	99 Years	Urgent	> 50.00	umol/L

Special Info

Patients should not have already received Vitamin B12 replacement therapy.

Clinical Info

Confirmation of vitamin B12 deficiency when vitamin levels are equivocal