Monoclonal Protein, 24 Hour Urine
Test Mnemonic
U24MPA
CPT Codes
- 86335 - QTY (1)
Aliases
- Immunoelectrophoresis, Urine
- Immunofixation Electrophoresis [IFE], Urine
- Myeloma Typing, Urine
Includes
- Interpretation
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 15 mL | Urine, 24-hour (well-mixed) | Clean container | Refrigerate during collection. | Refrigerated |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 7 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 1 day |
| Refrigerated | 14 days |
| Frozen | 30 days |
Days Performed
Mon - Fri
Turnaround Time
1 - 7 days
Methodology
| Name | Description |
|---|---|
| Immunofixation |
Reference Range
| Monoclonal Protein | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Free monoclonal light chains are not identified |
Special Info
Refrigerate during collection.
Clinical Info
Evaluation of monoclonal gammopathies, light chain amyloid disease, and serum hypogammaglobulinemia. Individuals with normal kidney function may have no protein or a trace of albumin in their urine. Kappa degradation fragments are benign fragments of light chains that may be seen in some normal urine samples. Monoclonal free immunoglobulin light chains may be seen in the urine even when not present in the serum, and may co-exist with an intact monoclonal immunoglobulin.