N-methyl-D-Aspartate Receptor Antibody, IgG
Test Mnemonic
NMDAG
CPT Codes
- 86255 - QTY (1)
Aliases
- Glutamate Receptor Antibodies
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | SST (Gold) | Refrigerated | Separate serum from cells within 2 hours of collection. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.15 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | After separation from cells: 2 days |
| Frozen | After separation from cells: 1 year |
| Refrigerated | After separation from cells: 2 weeks |
Days Performed
Tue, Fri
Turnaround Time
2 - 6 days
Methodology
| Name | Description |
|---|---|
| Semi-Quantitative Cell-Based Indirect Fluorescent Antibody |
Reference Range
| N-methyl-D-Aspartate Receptor Antibody, IgG | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Freetext | < 1:10 |
Special Info
If NMDA antibody IgG is positive, then an NMDA antibody IgG titer will be performed at an additional cost.
Clinical Info
Anti-NMDA receptor IgG antibodies are found in a subset of patients with autoimmune limbic encephalitis and may occur with or without associated tumor. Decreasing antibody levels may be associated to therapeutic response, therefore clinical correlation must be strongly considered. A negative test result does not rule out a diagnosis of autoimmune limbic encephalitis.