Pipecolic Acid, Serum
Test Mnemonic
PIPE
CPT Codes
- 82542 - QTY (1)
LOINC ®
32334-5
Includes
- Pipecolic Acid, S
- Interpretation
Performing Laboratory
Mayo Clinic Dpt of Lab Med & Pathology
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1.5 mL | Serum | SST (Gold) | Frozen | Patient should fast for at least 12 hours. Infant specimens should be collected just before feeding. Centrifuge, aliquot and freeze within 45 minutes of collection. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1.5 mL | Serum | No additive (Red) | Frozen | Patient should fast for at least 12 hours. Infant specimens should be collected just before feeding. Centrifuge, aliquot, and freeze within 45 minutes of collection. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | Unacceptable |
| Refrigerated | 14 days |
| Frozen | 94 days |
Days Performed
Thu
Turnaround Time
3 - 10 days
Methodology
| Name | Description |
|---|---|
| Gas Chromatography Mass Spectrometry (GCMS) |
Reference Range
| Pipecolic Acid, Serum | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Months | 5 Months | Normal | <= 6.0 | nmol/mL | 6 Months | 11 Months | Normal | <= 5.9 | nmol/mL | 1 Years | 17 Years | Normal | <= 4.3 | nmol/mL | 18 Years | 99 Years | Normal | <= 7.4 | nmol/mL |
Special Info
This test is New York DOH approved.
Clinical Info
Useful for the differential diagnosis between disorders of peroxisomal biogenesis and disorders with loss of a single peroxisomal function. Elevated levels are seen in disorders of peroxisomal biogenesis; normal levels are seen in disorders with loss of a single peroxisomal function. Abnormal results may reflect either prematurity or nongenetic liver and/or renal disease. CAUTION: Newborns with disorders of peroxisomal biogenesis often have normal levels of pipecolic acid which increase with age.