Plasminogen Activator Inhibitor, Activity




Test Mnemonic

PAI

CPT Codes

  • 85415 - QTY (1)

LOINC ®

5975-8

Aliases

  • PAI
  • Plasminogen Activator Inhibitor 1, Activity

Performing Laboratory

ARUP


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1.5 mLPlasmaSodium citrate (Lt. Blue) Frozen, CriticalCollect specimen between 8:00 a.m. - 12:00 noon. Separate plasma from cells within 1 hour of collection.

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mL     

Stability

Environmental Condition Description
Ambient1 hour
RefrigeratedUnacceptable
Frozen2 months

Days Performed

Mon, Thu

Turnaround Time

2 - 9 days

Methodology

Name Description
Bioimmunoactivity 

Reference Range

Special Info

Plasminogen Activator Inhibitor 1 (PAI-1) has diurnal variation, with higher concentration in the morning and decreased concentration in the afternoon. PAI-1 is also an acute phase reactant. The reference interval was established from fasting samples drawn between 8am and 12pm.

Clinical Info

This assay was designed primarily to identify elevated PAI-1 concentrations, which are thought to be a thrombotic risk factor. Concentrations below 2.0 IU/mL are not accurately quantified by this assay. A test result of <2.0 IU/mL is not diagnostic of PAI-1 deficiency and may be seen in normal individuals.