Platelet Function Screen
Test Mnemonic
PLTSCP
CPT Codes
- 85049 - QTY (1)
- 85014 - QTY (1)
- 85576 - QTY (2)
Aliases
- Platelet Closure Time
Includes
- COL/EPI closure time
- COL/ADP closure time
- Hematocrit
- Platelet Count
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 7 mL | Whole blood | Sodium citrate (Lt. Blue) | Ambient | Test must be completed within 4 hours of collection. | |
| 2.5 mL | Blood, peripheral | EDTA (Lavender) | Fill tube to at least half of fill volume. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 4.5 mL | Sodium citrate (Lt. Blue) tube. Test must be completed within 4 hours of collection. | ||||
| Unspecified | EDTA (Lavender) tube. Collection tube must be filled to at least half of fill volume. Minimum volume of 0.5 mL is needed for testing. |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 4 hours |
Days Performed
Sun - Sat
Turnaround Time
1 day
Methodology
| Name | Description |
|---|---|
| Platelet Aggregation/Adhesion |
Reference Range
| COL/ADP closure time | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | < 118 CT | sec | |||
| COL/EPI closure time | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Normal | < 194 CT | sec |
Special Info
3.2% sodium citrate is the preferred anticoagulant recommended by NCCLS.
Clinical Info
This test is useful in screening for platelet dysfunction, von Willebrand disease or the effect of anti-platelet drugs, especially aspirin. The test results may be prolonged with thrombocytopenia (less than 150,000/uL).