Pneumococcal IgG Antibodies, 23 Serotypes




Test Mnemonic

PNE23

CPT Codes

  • 86317 - QTY (23)

Aliases

  • Streptococcus pneumoniae Antibodies

Includes

  • Streptococcus pneumoniae Serotype 1 Abs
  • Streptococcus pneumoniae Serotype 2 Abs
  • Streptococcus pneumoniae Serotype 3 Abs
  • Streptococcus pneumoniae Serotype 4 Abs
  • Streptococcus pneumoniae Serotype 5 Abs
  • Streptococcus pneumoniae Serotype 6B Abs
  • Streptococcus pneumoniae Serotype 7F Abs
  • Streptococcus pneumoniae Serotype 8 Abs
  • Streptococcus pneumoniae Serotype 9N Abs
  • Streptococcus pneumoniae Serotype 9V Abs
  • Streptococcus pneumoniae Serotype 10A Abs
  • Streptococcus pneumoniae Serotype 11A Abs
  • Streptococcus pneumoniae Serotype 12F Abs
  • Streptococcus pneumoniae Serotype 14 Abs
  • Streptococcus pneumoniae Serotype 15B Abs
  • Streptococcus pneumoniae Serotype 17F Abs
  • Streptococcus pneumoniae Serotype 18C Abs
  • Streptococcus pneumoniae Serotype 19A Abs
  • Streptococcus pneumoniae Serotype 19F Abs
  • Streptococcus pneumoniae Serotype 20 Abs
  • Streptococcus pneumoniae Serotype 22F Abs
  • Streptococcus pneumoniae Serotype 23F Abs
  • Streptococcus pneumoniae Serotype 33F Abs

Performing Laboratory

ARUP


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1.5 mLSerumSST (Gold) RefrigeratedPost-immunization specimen should be drawn 30 days after immunization and must be received within 60 days of pre-immunization specimen. Label specimens clearly as 'Pre' or 'Post.' Separate serum from cells ASAP or within 2 hours of collection and transfer into standard aliquot tube.

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.25 mL     

Stability

Environmental Condition Description
AmbientAfter separation from cells: 48 hours
FrozenAfter separation from cells: 60 days (Avoid repeated freeze/thaw cycles)
RefrigeratedAfter separation from cells: 2 weeks

Days Performed

Tue, Fri

Turnaround Time

2 - 6 days

Methodology

Name Description
Quantitative Multiplex Chemiluminescent Immunoassay 

Reference Range

Special Info

Post-immunization specimen should be drawn 30 days after immunization and, if shipped separately, must be received within 60 days of pre-immunization specimen. Pre-immunization samples will be held and tested simultaneously with post-immunization samples. Plasma or other body fluids will be rejected. Contaminated, hemolyzed, or severely lipemic specimens are unacceptable. This test is New York DOH approved.

Clinical Info

A pre- and post-vaccination comparison is required to adequately assess the humoral immune response to Prevnar 7 (P7), Prevnar 13 (P13), and/or Pneumovax 23 (PNX) Streptococcus pneumoniae vaccines. Pre-vaccination samples should be collected prior to vaccine administration. Post-vaccination samples should be obtained at least 4 weeks after immunization. Testing of post-vaccination samples alone will provide only general immune status of the individual to various pneumococcal serotypes.