Pneumococcal IgG Antibodies, 23 Serotypes
Test Mnemonic
PNE23
CPT Codes
- 86317 - QTY (23)
Aliases
- Streptococcus pneumoniae Antibodies
Includes
- Streptococcus pneumoniae Serotype 1 Abs
- Streptococcus pneumoniae Serotype 2 Abs
- Streptococcus pneumoniae Serotype 3 Abs
- Streptococcus pneumoniae Serotype 4 Abs
- Streptococcus pneumoniae Serotype 5 Abs
- Streptococcus pneumoniae Serotype 6B Abs
- Streptococcus pneumoniae Serotype 7F Abs
- Streptococcus pneumoniae Serotype 8 Abs
- Streptococcus pneumoniae Serotype 9N Abs
- Streptococcus pneumoniae Serotype 9V Abs
- Streptococcus pneumoniae Serotype 10A Abs
- Streptococcus pneumoniae Serotype 11A Abs
- Streptococcus pneumoniae Serotype 12F Abs
- Streptococcus pneumoniae Serotype 14 Abs
- Streptococcus pneumoniae Serotype 15B Abs
- Streptococcus pneumoniae Serotype 17F Abs
- Streptococcus pneumoniae Serotype 18C Abs
- Streptococcus pneumoniae Serotype 19A Abs
- Streptococcus pneumoniae Serotype 19F Abs
- Streptococcus pneumoniae Serotype 20 Abs
- Streptococcus pneumoniae Serotype 22F Abs
- Streptococcus pneumoniae Serotype 23F Abs
- Streptococcus pneumoniae Serotype 33F Abs
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1.5 mL | Serum | SST (Gold) | Refrigerated | Post-immunization specimen should be drawn 30 days after immunization and must be received within 60 days of pre-immunization specimen. Label specimens clearly as 'Pre' or 'Post.' Separate serum from cells ASAP or within 2 hours of collection and transfer into standard aliquot tube. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.25 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | After separation from cells: 48 hours |
| Frozen | After separation from cells: 60 days (Avoid repeated freeze/thaw cycles) |
| Refrigerated | After separation from cells: 2 weeks |
Days Performed
Tue, Fri
Turnaround Time
2 - 6 days
Methodology
| Name | Description |
|---|---|
| Quantitative Multiplex Chemiluminescent Immunoassay |
Reference Range
Special Info
Post-immunization specimen should be drawn 30 days after immunization and, if shipped separately, must be received within 60 days of pre-immunization specimen. Pre-immunization samples will be held and tested simultaneously with post-immunization samples. Plasma or other body fluids will be rejected. Contaminated, hemolyzed, or severely lipemic specimens are unacceptable. This test is New York DOH approved.
Clinical Info
A pre- and post-vaccination comparison is required to adequately assess the humoral immune response to Prevnar 7 (P7), Prevnar 13 (P13), and/or Pneumovax 23 (PNX) Streptococcus pneumoniae vaccines. Pre-vaccination samples should be collected prior to vaccine administration. Post-vaccination samples should be obtained at least 4 weeks after immunization. Testing of post-vaccination samples alone will provide only general immune status of the individual to various pneumococcal serotypes.