Polio Neutralization
Test Mnemonic
PNEUT
CPT Codes
- 86658 - QTY (2)
Aliases
- Poliovirus (Types 1,3) Antibodies
Includes
- Poliovirus Type 3
- Poliovirus Type 1
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | SST (Gold) | Refrigerated | Separate from cells ASAP or within 2 hours of collection. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | No additive (Red) | Refrigerated | Separate from cells ASAP or within 2 hours of collection. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.2 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | After separation from cells: 48 hours |
| Refrigerated | After separation from cells: 2 weeks |
| Frozen | After separation from cells: 1 year (Avoid repeated freeze/thaw cycles) |
Days Performed
Mon - Fri
Turnaround Time
7 - 13 days
Methodology
| Name | Description |
|---|---|
| Neutralization |
Reference Range
| Polio 1 | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 99 Years | Normal | <1:10 | titer | |
| Polio 3 | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 99 Years | Normal | <1:10 | titer |
Special Info
Unacceptable conditions: Plasma. Contaminated, hemolyzed, or severely lipemic specimens. This test is New York DOH approved.
Clinical Info
The presence of neutralizing antibodies against poliovirus implies immunity. The serum neutralization test is serotype specific. Antibodies against one type does not indicate immunity against the other type. Results >= 1:10 titer indicates an antibody to Poliovirus is detected, which may represent prior immunization or current or past infection.