Prenatal Quad Screen
Test Mnemonic
QUAD4
CPT Codes
- 82105 - QTY (1)
- 84702 - QTY (1)
- 82677 - QTY (1)
- 86336 - QTY (1)
LOINC ®
49092-0
Aliases
- AFP Quad Check
- AFP4
Includes
- AFP (maternal)
- HCG
- Estriol
- Inhibin A
Performing Laboratory
Cleveland Clinic Laboratories
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 2 mL | Serum | SST (Gold) | Refrigerated | Submit a Prenatal screen requisition with specimen. Complete clinical and demographic information is required for reporting. Specimen must be drawn between 15.0 weeks - 21.6 weeks gestation. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Submit a Prenatal screen requisition with specimen. Complete clinical and demographic information is required for reporting. Specimen must be drawn between 15.0 weeks - 21.6 weeks gestation. |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 1 day |
| Refrigerated | 7 days |
| Frozen | 14 days |
Days Performed
Mon - Fri
Turnaround Time
1 - 3 days
Methodology
| Name | Description |
|---|---|
| Chemiluminescence Immunoassay (CLIA) |
Reference Range
| AFP (maternal) | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Screen Negative |
Special Info
Submit a Prenatal screen requisition with specimen. Complete clinical and demographic information is required for reporting. Specimen must be drawn between 15.0 weeks - 21.9 weeks (21 weeks 6 days) gestation.
Clinical Info
Risk assessment for birth defects: open neural tube, fetal Downs Syndrome, and Trisomy 18.