Prometheus IBD sgi Diagnostic




Test Mnemonic

IBDSGI

CPT Codes

  • 83520 - QTY (6)
  • 82397 - QTY (4)
  • 86140 - QTY (1)
  • 88346 - QTY (1)
  • 88350 - QTY (1)
  • 81479 - QTY (4)

Includes

  • ASCA IgA
  • ASCA IgG
  • Anti OMPC IgA
  • Anti CBir1 IgG
  • Anti A4 Fla2 IgG
  • Anti FlaX IgG
  • IBD Specific pANCA Autoab
  • IBD Specific pANCA IFA Perinuclear Pattern
  • IBD Specific pANCA DNAse Sensitivity
  • ATG16L1 SNP
  • ECM1 SNP
  • NKX2-3 SNP
  • STAT3 SNP
  • ICAM-1
  • VCAM-1
  • VEGF
  • CRP
  • SAA

Performing Laboratory

Prometheus


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
2 mLSerumSST (Gold) RefrigeratedTHIS TEST REQUIRES MULTIPLE SPECIMEN TYPES.
2 mLWhole bloodEDTA (Lavender) RefrigeratedTHIS TEST REQUIRES MULTIPLE SPECIMEN TYPES.

Alternate Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
2 mLWhole bloodEDTA (Lavender) RefrigeratedTHIS TEST REQUIRES MULTIPLE SPECIMEN TYPES.
2 mLSerumNo additive (Red) RefrigeratedTHIS TEST REQUIRES MULTIPLE SPECIMEN TYPES.

Stability

Environmental Condition Description
Ambient1 week
Refrigerated3 weeks
FrozenUnacceptable

Days Performed

Mon - Fri

Turnaround Time

4 - 6 days

Methodology

Name Description
Enzyme-Linked Immunosorbent Assay (ELISA) 
Indirect Immunofluorescence Assay (IFA)  
Polymerase Chain Reaction (PCR) 
Chemiluminescence (CL) 

Reference Range

Anti A4 Fla2 IgG
Sex Age From Age To Type Range Range Unit
       < 32.4 EU/mL 
Anti CBir1 IgG
Sex Age From Age To Type Range Range Unit
       < 35.4 EU/mL 
Anti FlaX IgG
Sex Age From Age To Type Range Range Unit
       < 36.0 EU/mL 
Anti OMPC IgA
Sex Age From Age To Type Range Range Unit
       < 11.3 EU/mL 
ASCA IgA
Sex Age From Age To Type Range Range Unit
       < 9.2 EU/mL 
ASCA IgG
Sex Age From Age To Type Range Range Unit
       < 11.9 EU/mL 
CRP
Sex Age From Age To Type Range Range Unit
       < 13.4 mg/L 
IBD Specific pANCA Autoab
Sex Age From Age To Type Range Range Unit
       < 30.1 EU/mL 
ICAM-1
Sex Age From Age To Type Range Range Unit
       < 0.52 ug/mL 
SAA
Sex Age From Age To Type Range Range Unit
       < 22.9 mg/L 
STAT3 SNP
Sex Age From Age To Type Range Range Unit
       Mutation Detected 
VCAM-1
Sex Age From Age To Type Range Range Unit
       < 0.75 ug/mL 
VEGF
Sex Age From Age To Type Range Range Unit
       < 393 pg/mL 

Special Info

THIS TEST REQUIRES MULTIPLE SPECIMEN TYPES.

Clinical Info

Sensitivity: IBD 74%; UC 98%; CD 89%. Specificity: IBD 90%; UC 83%; CD 81%. Patient test results are based on the Smart Diagnostic Algorithm which interprets complex patterns among assay values from a combination of serologic, genetic, and inflammatory markers.