Prothrombin Time Mixing Study | Cleveland Clinic Laboratories

Prothrombin Time Mixing Study Print

Test Mnemonic

PTMIX

CPT Codes

85610 - QTY (1)
85390 - QTY (1)

Aliases

PT Mixing Studies
PT Correction Studies

Includes

PT Screen

Performing Laboratory

Cleveland Clinic Laboratories

Specimen Requirements

Volume	Type	Container	Collect Temperature	Transport Temperature	Special Instructions
6 mL	Plasma	Sodium citrate (Lt. Blue)		Centrifuge, aliquot and freeze ASAP.	Non-Testing Sites: Centrifuge samples; Aliquot plasma into a separate tube and label with Epic Beaker labels. Specimens should be frozen (-20° C or colder).

Minimum Specimen Requirements

Volume	Type	Container	Collect Temperature	Transport Temperature	Special Instructions
2 mL					Minimum is 2 mL of plasma. NOTE: If only the minimum volume is received, some reflex testing may not be able to be performed.

Stability

Environmental Condition	Description
Ambient	Main campus: ACCEPTABLE for Whole Blood. (Must be delivered ambient to testing lab less than 4 hours post collection.) Non-Testing Sites: UNACCEPTABLE.
Refrigerated	Unacceptable
Frozen	For Non-Testing sites, Frozen Plasma is ACCEPTABLE. (Centrifuge samples, then aliquot plasma into a separate tube and label with Epic Beaker labels. Specimens should be frozen (-20° C or colder) and they are stable for 2 months.

Days Performed

Mon - Fri

Turnaround Time

1 - 3 days

Methodology

Name	Description
Clot Detection

Reference Range

PT Screen
Sex	Age From	Age To	Type	Range	Range Unit
	Days	1 Days	Normal	< 14.9	sec
	1 Months	3 Months	Normal	< 13.3	sec
	2 Days	5 Days	Normal	< 14.3	sec
	6 Days	30 Days	Normal	< 13.4	sec
	4 Months	11 Months	Normal	< 13.0	sec
	1 Years	5 Years	Normal	< 10.7	sec
	6 Years	10 Years	Normal	< 11.3	sec
	11 Years	16 Years	Normal	< 11.2	sec
	17 Years	99 Years	Normal	< 13.1	sec

Special Info

If tests are abnormal in the panel, the following tests may be ordered and billed: Factor II (85210) , Factor V (85220), Factor VII (85230), Factor X (85260), Factor VIII (85247), Factor VIII Chromogenic (85240), Factor IX Assay (85250), Factor XI Assay (85270), Factor XII Assay (85280), Reptilase Time (85635), D-Dimer (85379), Thrombin Time (85670), Fibrinogen (85384), Bethesda Inhibitor (85335), Factor XIII Antigen (85290), Lupus Panel, DRVVT (85613 x2), STACLOT (85730 & 85732), Platelet Neutralization (85597), Anti-Xa (85520) & Fibrinogen Ag (85385).

Clinical Info

To distinguish a coagulation factor deficiency from an inhibitor.