Prothrombin Time Mixing Study




Test Mnemonic

PTMIX

CPT Codes

  • 85610 - QTY (1)
  • 85390 - QTY (1)

Aliases

  • PT Mixing Studies
  • PT Correction Studies

Includes

  • PT Screen

Performing Laboratory

n/a


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
6 mLPlasmaSodium citrate (Lt. Blue) Centrifuge, aliquot and freeze ASAP.Non-Testing Sites: Centrifuge samples; Aliquot plasma into a separate tube and label with Epic Beaker labels. Specimens should be frozen (-20° C or colder).

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
2 mL    Minimum is 2 mL of plasma. NOTE: If only the minimum volume is received, some reflex testing may not be able to be performed.

Stability

Environmental Condition Description
AmbientMain campus: ACCEPTABLE for Whole Blood. (Must be delivered ambient to testing lab less than 4 hours post collection.) Non-Testing Sites: UNACCEPTABLE.
RefrigeratedUnacceptable
FrozenFor Non-Testing sites, Frozen Plasma is ACCEPTABLE. (Centrifuge samples, then aliquot plasma into a separate tube and label with Epic Beaker labels. Specimens should be frozen (-20° C or colder) and they are stable for 2 months.

Days Performed

Mon - Fri

Turnaround Time

1 - 3 days

Methodology

Name Description
Clot Detection 

Reference Range

PT Screen
Sex Age From Age To Type Range Range Unit
   Days1 DaysNormal< 14.9sec
 1 Months3 MonthsNormal< 13.3sec
 2 Days5 DaysNormal< 14.3sec
 6 Days30 DaysNormal< 13.4sec
 4 Months11 MonthsNormal< 13.0sec
 1 Years5 YearsNormal< 10.7sec
 6 Years10 YearsNormal< 11.3sec
 11 Years16 YearsNormal< 11.2sec
 17 Years99 YearsNormal< 13.1sec

Special Info

If tests are abnormal in the panel, the following tests may be ordered and billed: Factor II (85210) , Factor V (85220), Factor VII (85230), Factor X (85260), Factor VIII (85247), Factor VIII Chromogenic (85240), Factor IX Assay (85250), Factor XI Assay (85270), Factor XII Assay (85280), Reptilase Time (85635), D-Dimer (85379), Thrombin Time (85670), Fibrinogen (85384), Bethesda Inhibitor (85335), Factor XIII Antigen (85290), Lupus Panel, DRVVT (85613 x2), STACLOT (85730 & 85732), Platelet Neutralization (85597), Anti-Xa (85520) & Fibrinogen Ag (85385).

Clinical Info

To distinguish a coagulation factor deficiency from an inhibitor.