PSA, Free




Test Mnemonic

PSATF

CPT Codes

  • 84154 - QTY (1)

LOINC ®

10886-0

Aliases

  • Prostate Specific Antigen, Free

Includes

  • PSA
  • PSA Percent Free

Performing Laboratory

Cleveland Clinic Laboratories


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mLPlasmaLithium heparin PST (Lt. Green) Refrigerated 

Alternate Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mLSerumSST (Gold)   

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.5 mL     

Stability

Environmental Condition Description
Ambient8 hours
Refrigerated5 days
Frozen3 months

Days Performed

Sun - Sat

Turnaround Time

8 hours

Methodology

Name Description
Electro Chemiluminescence Immunoassay (ECLIA) 

Reference Range

PSA
Sex Age From Age To Type Range Range Unit
Male      Normal<2.6ng/mL
       Note: See Special Info section 
PSA, Percent Free
Sex Age From Age To Type Range Range Unit
       See comment 
       See comment 

Special Info

For an individual patient, the significance of a PSA level should be interpreted in a broad clinical context, including age, race, family history, digital rectal exam, prostate size, results of prior testing (prostate biopsy, free PSA, PCA3), and use of 5-alpha reductase inhibitors. Considering the high incidence of asymptomatic cancer in the general population that may not pose an ultimate risk to the patient, the decision to recommend urological evaluation or prostate biopsy should be individualized after considering all of these factors. Reference: Punglia S, Rinaa, M.D., M.P.H., D'Amico V, Anthony, M.D., Ph.D., Catalona J, William, M.D., Roehl A, Kimberly, M.P.H., Kuntz M., Karen, Sc.D. Effect of Verification Bias on Screening for Prostate Cancer Measurement of Prostate-Specific Antigen. N Engl J Med 2003;349:335-42. Add-ons will only be accepted from the emergency department providing an unopened/unprocessed tube is available for testing.

Clinical Info

In conjunction with total PSA, used as an aid in distinguishing prostate cancer from a benign prostate condition. Total and free PSA test methodology used is the electrochemiluminescence immunoassay by Roche Diagnostics. Total or free PSA values by differing methodologies cannot be interchanged.