PTH Related Peptide
Test Mnemonic
PTHPEP
CPT Codes
- 82542 - QTY (1)
- 82397 - QTY (1)
LOINC ®
15087-0
Aliases
- Parathyroid Hormone Related Peptide
- PTHrP by LC-MS/MS, Plasma
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1.5 mL | Plasma | Protease Inhibitor Tube | Centrifuge, aliquot and freeze ASAP. | Collect using Protease Inhibitor tube (PPACK; Phe-Pro-Arg-chloromethylketone) (ARUP supply #49662). A winged collection set must be used. Mix well. Separate from cells within one hour of collection. Transfer 1.5 mL plasma to standard aliquot tube and freeze immediately. Separate specimens must be submitted when multiple tests are ordered. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.7 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Frozen | After separation from cells: 3 months |
| Ambient | After separation from cells: Unacceptable |
| Refrigerated | After separation from cells: Unacceptable |
Days Performed
Sun, Mon, Wed, Fri
Turnaround Time
3 - 7 days
Methodology
| Name | Description |
|---|---|
| High Performance Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS) |
Reference Range
| PTH Related Peptide | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Male (Under 18 Years): Not established | Male (18 Years and older): 0.0 - 2.3 pmol/L | Female (Under 18 Years): Not established | Female (18 Years and older): 0.0 - 3.4 pmol/L |
Special Info
Grossly hemolyzed specimens are unacceptable. This test is New York DOH approved.
Clinical Info
Aids in the evaluation of unexplained hypercalcemia, particularly in suspected hypercalcemia of malignancy. Amino (N)- and carboxy (C)-terminus PTHrP fragments, such as those produced by some patients with renal insufficiency, do not interfere with this assay.