PTH Related Peptide




Test Mnemonic

PTHPEP

CPT Codes

  • 82542 - QTY (1)
  • 82397 - QTY (1)

LOINC ®

15087-0

Aliases

  • Parathyroid Hormone Related Peptide
  • PTHrP by LC-MS/MS, Plasma

Performing Laboratory

ARUP


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1.5 mLPlasmaProtease Inhibitor Tube Centrifuge, aliquot and freeze ASAP.Collect using Protease Inhibitor tube (PPACK; Phe-Pro-Arg-chloromethylketone) (ARUP supply #49662). A winged collection set must be used. Mix well. Separate from cells within one hour of collection. Transfer 1.5 mL plasma to standard aliquot tube and freeze immediately. Separate specimens must be submitted when multiple tests are ordered.

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.7 mL     

Stability

Environmental Condition Description
FrozenAfter separation from cells: 3 months
AmbientAfter separation from cells: Unacceptable
RefrigeratedAfter separation from cells: Unacceptable

Days Performed

Sun, Mon, Wed, Fri

Turnaround Time

3 - 7 days

Methodology

Name Description
High Performance Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS) 

Reference Range

PTH Related Peptide
Sex Age From Age To Type Range Range Unit
       Male (Under 18 Years): Not established 
       Male (18 Years and older): 0.0 - 2.3 pmol/L 
       Female (Under 18 Years): Not established 
       Female (18 Years and older): 0.0 - 3.4 pmol/L 

Special Info

Grossly hemolyzed specimens are unacceptable. This test is New York DOH approved.

Clinical Info

Aids in the evaluation of unexplained hypercalcemia, particularly in suspected hypercalcemia of malignancy. Amino (N)- and carboxy (C)-terminus PTHrP fragments, such as those produced by some patients with renal insufficiency, do not interfere with this assay.