Quetiapine
Test Mnemonic
QUETIA
CPT Codes
- 80342/G0480 - QTY (1)
Aliases
- Seroquel
Includes
- Quetiapine, Serum/Plasma
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | No additive (Red) | Refrigerated | Do not use serum separator tubes. Separate serum from cells within 2 hours and transfer to standard aliquot tube. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Plasma | EDTA (Lavender) | Refrigerated | Do not use plasma separator tubes. Separate plasma from cells within 2 hours and transfer to standard aliquot tube. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 24 hours |
| Refrigerated | 2 weeks |
| Frozen | 4 months |
Days Performed
Wed
Turnaround Time
2 - 9 days
Methodology
| Name | Description |
|---|---|
| Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) |
Reference Range
| Quetiapine | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Therapeutic Range: 100-1000 ng/mL | Toxic: Greater than 1000 ng/mL |
Special Info
Unspun specimens and gel separator tubes will be rejected. This test is New York state approved.
Clinical Info
This test is useful to optimize drug therapy and monitor patient adherence. Quetiapine is an antipsychotic drug indicated for the treatment of schizophrenia and bipolar disorder. The pharmacokinetics of quetiapine are influenced by drug-drug interactions that may inhibit or induce CYP3A4 metabolism. Adverse effects may include somnolence, hypotension, dizziness, fatigue, constipation, weight gain.