RNA Polymerase III Ab, IgG
Test Mnemonic
RNAIII
CPT Codes
- 83516 - QTY (1)
LOINC ®
53893-4
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | SST (Gold) | Refrigerated | Centrifuge and aliquot within 2 hours of collection. |
Alternate Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1 mL | Serum | No additive (Red) | Refrigerated | Centrifuge and aliquot within 2 hours of collection. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.2 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | After separation from cells: 2 days |
| Refrigerated | After separation from cells: 2 weeks |
| Frozen | After separation from cells: 1 year |
Days Performed
Tue, Thu, Sun
Turnaround Time
2 - 5 days
Methodology
| Name | Description |
|---|---|
| Enzyme-Linked Immunosorbent Assay (ELISA) |
Reference Range
| RNA POLYMERASE III AB IgG | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Years | 99 Years | Normal | 0 - 19 | Units |
Special Info
Centrifuge and aliquot within 2 hours of collection.
Clinical Info
Interpretative data: Negative: 0 - 19 Units; Weak Positive: 20 - 39 Units; Moderate Positive: 40 - 80 Units; Strong Positive: >80 Units. Elevated RNA polymerase III IgG antibodies are found primarily in a subset of systemic sclerosis (SSc) patients who are typically negative for anti-centromere and anti-Scl-70 antibodies, and which may be predictive of increased risk for skin involvement and hypertensive renal failure associated with the diffuse cutaneous form of scleroderma.