RPR with Titer




Test Mnemonic

RPRT

CPT Codes

  • 86592 - QTY (1)

Aliases

  • Monitor treatment if positive Syphilis

Performing Laboratory

Cleveland Clinic Laboratories


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mLSerumSST (Gold) Refrigerated 

Alternate Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.5 mLSerumNo additive (Red) Refrigerated 

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.5 mL     

Stability

Environmental Condition Description
Refrigerated7 days
Ambient1 day
Frozen14 days

Days Performed

Sun - Sat

Methodology

Name Description
Flocculation 

Reference Range

Special Info

If Reactive, then RPR Quant Titer will be ordered and charged. When a reactive specimen is found, Ohio state law requires completion of an Ohio Department of Health confidential report form.

Clinical Info

Rapid Plasma Reagin (RPR) is a semi-quantitative non-treponemal test that is only used when syphilis screen (i.e., treponemal) test is positive/reactive. RPR is also used for treatment follow up of treponemal infections mainly venereal syphilis. RPR may be reactive due to a range of other causes, certain infections (HIV, tuberculosis, malaria, etc.), anti-phospholipid syndrome, endocarditis, and malignancies among others. Clinical correlation is required.