Saccharomyces cerevisiae IgG & IgA
Test Mnemonic
SACHAR
CPT Codes
- 86671 - QTY (2)
Includes
- S. Cervisiae Ab IgG
- S. Cerevisiae Ab IgA
Performing Laboratory
ARUP
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.5 mL | Serum | SST (Gold) | Refrigerated | Centrifuge, aliquot and refrigerate ASAP or within 2 hours of collection. |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 0.3 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | After separation from cells: 2 days |
| Refrigerated | After separation from cells: 2 weeks |
| Frozen | After separation from cells:1 year |
Days Performed
Sun - Sat
Turnaround Time
2 - 3 days
Methodology
| Name | Description |
|---|---|
| Enzyme-Linked Immunosorbent Assay (ELISA) |
Reference Range
| S. Cerevisiae Ab IgA | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Negative: < = 20 Units | Positive: >= 25 Units | Equivocal: 20.1 - 24.9 Units | |||
| S. Cervisiae Ab IgG | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Negative: < = 20 Units | Positive: >= 25 Units | Equivocal: 20.1 - 24.9 Units |
Special Info
Unacceptable: severely lipemic, contaminated, heat-inactivated or hemolyzed specimens.
Clinical Info
Saccharomyces Cerevisiae IgG antibodies are found in 60 - 70 % of Crohn disease (CD) patients, and 10 - 15 % of ulcerative colitis (UC) patients. Saccharomyces Cerevisiae IgA antibodies are found in 35% of CD patients but less than 1% in UC patients. Detection of both Saccharomyces IgG and IgA antibodies in the same serum specimen is highly specific for CD.