Synthetic Glucocorticoid Screen, Serum
Test Mnemonic
SGLUCO
CPT Codes
- 82542 - QTY (1)
Includes
- Betamethasone
- Budesonide
- Dexamethasone
- Fludrocortisone
- Flunisolide
- Fluorometholone
- Megestrol acetate
- Methylprednisolone
- Prednisolone
- Prednisone
- Triamcinolone
- Triamcinolone acetonide
Performing Laboratory
Mayo Clinic Dpt of Lab Med & Pathology
Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 2 mL | Serum | No additive (Red) | Frozen |
Minimum Specimen Requirements
| Volume | Type | Container | Collect Temperature | Transport Temperature | Special Instructions |
|---|---|---|---|---|---|
| 1.1 mL |
Stability
| Environmental Condition | Description |
|---|---|
| Ambient | 24 hours |
| Refrigerated | 7 days |
| Frozen | 14 days |
Days Performed
Tue, Fri
Turnaround Time
3 - 6 days
Methodology
| Name | Description |
|---|---|
| Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) | |
| Stable Isotope Dilution |
Reference Range
| Betamethasone | |||||
|---|---|---|---|---|---|
| Sex | Age From | Age To | Type | Range | Range Unit |
| Negative | |||||
| Budesonide | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Negative | |||||
| Dexmethasone | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Negative | |||||
| Fludrocortisone | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Negative | |||||
| Flunisolide | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Negative | |||||
| Fluorometholone | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Negative | |||||
| Megestrol Acetate | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Negative | |||||
| Methylprednisolone | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Negative | |||||
| Prednisolone | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Negative | |||||
| Prednisone | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Negative | |||||
| Triamcinolone | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Negative | |||||
| Triamcinolone Acetonide | |||||
| Sex | Age From | Age To | Type | Range | Range Unit |
| Negative |
Clinical Info
Cuttoff Concentrations: Betamethasone: 0.10 mcg/dL; Budesonide: 0.10 mcg/dL; Dexamethasone: 0.10 mcg/dL; Fludrocortisone: 0.10 mcg/dL; Flunisolide: 0.10 mcg/dL; Fluorometholone: 0.10 mcg/dL; Megestrol acetate: 0.10 mcg/dL; Methylprednisolone: 0.10 mcg/dL; Prednisolone: 0.10 mcg/dL; Prednisone: 0.10 mcg/dL; Triamcinolone: 0.30 mcg/dL; Triamcinolone acetonide: 0.10 mcg/dL. Lack of detection does not preclude use of synthetic glucocorticoid because adrenal suppression may persist for some time after the exogenous steroid is discontinued. This method cannot detect all the available synthetic steroids either available as pharmaceutical compounds or chemicals present in food. The assay confirms only the listed synthetic glucocorticoids.