Syphilis Total with reflex




Test Mnemonic

SYPHTX

CPT Codes

  • 86780 - QTY (1)

Aliases

  • T. pallidum
  • Treponema pallidum

Performing Laboratory

Cleveland Clinic Laboratories


Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
1 mLSerumSST (Gold) Refrigerated 

Minimum Specimen Requirements

Volume Type Container Collect Temperature Transport Temperature Special Instructions
0.5 mL    Submitting the minimum volume will not allow for repeat testing or addons. Required volume of 1 mL is preferred when possible.

Stability

Environmental Condition Description
Ambient3 days
Refrigerated7 days
Frozen30 days

Days Performed

Mon - Sat

Turnaround Time

1 - 3 days

Methodology

Name Description
Chemiluminescent Microparticle Immunoassay (CMIA) 

Reference Range

Special Info

Results in samples from immunosuppressed patients or from patients with disorders leading to immunosuppression should be interpreted with caution.

Clinical Info

This test is recommended as the screen in patients with clinical and/or epidemiological risk factors for contracting syphilis. Final interpretation should take into account the results from RPR and the confirmatory test, where indicated. A nonreactive result does not totally exclude a recent, within the past 2-3 weeks, Treponema pallidum infection. Detection of treponemal antibodies may indicate recent, past, or successfully treated syphilis infections and therefore cannot be used to differentiate between active and cured cases.

Clinical Limitation

Not intended for use in the screening of blood, plasma or tissue donors. Performance has not been established for the use of cadaveric specimens or the use of body fluids (other than serum). Avoid specimens with the following conditions: heat-inactivated, grossly hemolyzed (> 500 mg/dL hemoglobin), grossly lipemic, or obvious microbial contamination.